CAS: Catalysis with Cobalt Hydrides
CAS:氢化钴催化
基本信息
- 批准号:2349483
- 负责人:
- 金额:$ 59.5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2024
- 资助国家:美国
- 起止时间:2024-09-01 至 2027-08-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
With support from the Chemical Catalysis Program of the Division of Chemistry, Professor Hairong Guan and his group at the University of Cincinnati will examine the catalytic activities of cobalt hydrides. Catalysis plays an indispensable role in chemical synthesis for pharmaceutical, energy, and materials applications. Precious metals are often the metals of choice for designing catalysts. However, they are expensive, limited in supply, and sometimes difficult to remove from the products. In this project, Dr. Guan will focus on cobalt, an inexpensive and earth-abundant metal, to study the reactivity of molecules bearing cobalt-hydrogen bonds, which are poorly understood, but are key intermediates in many cobalt-catalyzed reactions. Through this project, Dr. Guan and his team will be actively engaged in outreach and training activities that benefit students from underrepresented groups, including those participating in the Undergraduates Pursuing Research in Science and Engineering Program at the University of Cincinnati and the ACS Project SEED Program as well as from collaborating predominantly undergraduate institutions. Dr. Guan will also develop research-based course materials and spectral resources that are expected to enhance the educational experience.In this project, Professor Hairong Guan and his research team aim to develop an understanding of how different ligand platforms impact the reactivity of cobalt hydrides. This research project will focus on elucidating the mechanistic details of hydrosilylation, hydroboration, and hydrophosphination reactions catalyzed by monophosphine-stabilized cobalt hydride complexes, and explore new reactions catalyzed by pincer-ligated cobalt hydrides. Also under investigation will be how pi-allyl and hydroxycyclopentadienyl cobalt complexes behave as masked hydrides in hydrogen transfer reactions as well as electrocatalysts for the reduction of carbon dioxide and the dehalogenation of chlorinated and fluorinated compounds. The proposed research studies are expected to contribute to the foundational knowledge of cobalt hydrides in catalysis. The lessons learned in these studies have the potential for broad scientific impact in the larger field of earth abundant transition metal catalysis.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
在化学系化学催化项目的支持下,辛辛那提的管海荣教授和他的小组将研究钴的催化活性。催化在化学合成中起着不可或缺的作用,用于制药,能源和材料应用。贵金属通常是设计催化剂的首选金属。然而,它们价格昂贵,供应有限,有时难以从产品中去除。在这个项目中,Guan博士将专注于钴,一种廉价且地球上丰富的金属,以研究具有钴-氢键的分子的反应性,这些分子知之甚少,但在许多钴催化反应中是关键中间体。通过这个项目,关博士和他的团队将积极参与外展和培训活动,使来自代表性不足群体的学生受益,包括那些参加辛辛那提大学的本科生追求科学和工程研究计划和ACS项目SEED计划的学生,以及来自合作的主要本科院校的学生。关博士还将开发基于研究的课程材料和光谱资源,预计将增强教育体验。在这个项目中,关海荣教授和他的研究团队旨在了解不同的配体平台如何影响钴的反应性。本研究计划将致力于阐明单膦稳定的氢化钴配合物催化的硅氢加成、硼氢加成和膦氢加成反应的机理细节,并探索钳形连接的钴配合物催化的新反应。此外,还将研究π-烯丙基和羟基钴络合物在氢转移反应中如何作为掩蔽的钴,以及用于还原二氧化碳和氯化和氟化化合物的脱卤的电催化剂。 所提出的研究有望有助于对钴催化剂的基础知识的了解。在这些研究中获得的经验教训有可能在地球丰富的过渡金属催化的更大领域产生广泛的科学影响。该奖项反映了NSF的法定使命,并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Hairong Guan其他文献
Using CS2 to Probe the Mechanistic Details of Decarboxylation of Bis(phosphinite)-Ligated Nickel Pincer Formate Complexes
使用 CS2 探讨双(次亚膦酸酯)连接的镍钳甲酸盐配合物脱羧的机理细节
- DOI:
10.1021/acs.organomet.6b00759 - 发表时间:
2016-12 - 期刊:
- 影响因子:2.8
- 作者:
Qiang-Qiang Ma;Ting Liu;Anubendu Adhikary;Jie Zhang;Jeanette A. Krause;Hairong Guan - 通讯作者:
Hairong Guan
Iron-Catalyzed Oppenauer-Type Oxidation of Alcohols.
铁催化醇的奥本诺型氧化。
- DOI:
10.1002/chin.201036037 - 发表时间:
2010 - 期刊:
- 影响因子:0
- 作者:
Michael G. Coleman;Alec N. Brown;Brett A. Bolton;Hairong Guan - 通讯作者:
Hairong Guan
Highly Efficient Reduction of Carbon Dioxide with a Borane Catalyzed by Bis(phosphinite) Pincer Ligated Palladium Thiolate Complexes
双(次亚膦酸酯)钳连接的硫醇钯配合物催化硼烷高效还原二氧化碳
- DOI:
10.1039/c6cc07987c - 发表时间:
2016 - 期刊:
- 影响因子:4.9
- 作者:
Qiang-Qiang Ma;Ting Liu;Shujun Li;Jie Zhang;Xuenian Chen;Hairong Guan - 通讯作者:
Hairong Guan
Mechanistic Study of Nickel-Catalyzed Reductive Coupling of Ynoates and Aldehydes.
镍催化乙醛与镍催化还原偶联的机理研究。
- DOI:
- 发表时间:
2017 - 期刊:
- 影响因子:3.6
- 作者:
S. K. Rodrigo;Hairong Guan - 通讯作者:
Hairong Guan
Synthesis and properties of carboxy-substituted half-sandwich ruthenium complexes with chelating bisphosphine ligands (η<sup>5</sup>-C<sub>5</sub>H<sub>4</sub>CO<sub>2</sub>H)Ru(η<sup>2</sup>-L)X (X = I, H)
- DOI:
10.1016/j.jorganchem.2008.01.030 - 发表时间:
2008-04-01 - 期刊:
- 影响因子:
- 作者:
Anthony P. Shaw;Hairong Guan;Jack R. Norton - 通讯作者:
Jack R. Norton
Hairong Guan的其他文献
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{{ truncateString('Hairong Guan', 18)}}的其他基金
CAS: Taming the Reactivity of Base Metal Hydrides Through Bifunctional Ligands
CAS:通过双功能配体控制贱金属氢化物的反应性
- 批准号:
2102192 - 财政年份:2021
- 资助金额:
$ 59.5万 - 项目类别:
Continuing Grant
Metal-Ligand and Metal-Metal Cooperativities as Design Principles for Base Metal Catalysis
金属-配体和金属-金属协同作用作为贱金属催化的设计原则
- 批准号:
1800151 - 财政年份:2018
- 资助金额:
$ 59.5万 - 项目类别:
Standard Grant
MRI: SusChEM: Acquisition of a 400 MHz Nuclear Magnetic Resonance (NMR) Spectrometer for Research and Education
MRI:SusChEM:购买 400 MHz 核磁共振 (NMR) 波谱仪用于研究和教育
- 批准号:
1726092 - 财政年份:2017
- 资助金额:
$ 59.5万 - 项目类别:
Standard Grant
MRI: Acquisition of a Single-Crystal X-ray Diffractometer for Chemical Crystallography Research and Training
MRI:购买单晶 X 射线衍射仪用于化学晶体学研究和培训
- 批准号:
1625737 - 财政年份:2016
- 资助金额:
$ 59.5万 - 项目类别:
Standard Grant
SusChEM: Catalytic Activation of Small Molecules by Nickel and Iron Pincer Complexes
SusChEM:镍和铁钳配合物催化活化小分子
- 批准号:
1464734 - 财政年份:2015
- 资助金额:
$ 59.5万 - 项目类别:
Standard Grant
CAREER: Nickel and Iron Complexes as Efficient and Selective Catalysts for Carbon Dioxide Reduction and Organic Synthesis
职业:镍和铁络合物作为二氧化碳还原和有机合成的高效选择性催化剂
- 批准号:
0952083 - 财政年份:2010
- 资助金额:
$ 59.5万 - 项目类别:
Continuing Grant
相似国自然基金
不对称Tandem catalysis 合成手性仲醇
- 批准号:20643008
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CAREER: Innovating Oxidative C–H Functionalization via Rhodium and Cobalt Catalysis
职业生涯:通过铑和钴催化创新氧化 C–H 功能化
- 批准号:
2340731 - 财政年份:2024
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$ 59.5万 - 项目类别:
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Cobalt Catalysis as an Inexpensive, Earth-Abundant Platform for the Synthesis of Pharmaceuticals
钴催化作为一种廉价、地球资源丰富的药物合成平台
- 批准号:
571186-2021 - 财政年份:2022
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$ 59.5万 - 项目类别:
Banting Postdoctoral Fellowships Tri-council
CAS: Four-Coordinate Iron- and Cobalt-Carbene Complexes for Carbene-Transfer Catalysis
CAS:用于卡宾转移催化的四配位铁和钴卡宾配合物
- 批准号:
2154892 - 财政年份:2022
- 资助金额:
$ 59.5万 - 项目类别:
Standard Grant
Lindau - Cobalt Catalysis as an Inexpensive, Earth-Abundant Platform for the Synthesis of Pharmaceuticals
Lindau - 钴催化作为一种廉价、地球资源丰富的药物合成平台
- 批准号:
577591-2022 - 财政年份:2022
- 资助金额:
$ 59.5万 - 项目类别:
Doctoral Prizes
Cobalt Catalysis as an Inexpensive, Earth-Abundant Platform for the Synthesis of Pharmaceuticals
钴催化作为一种廉价、地球资源丰富的药物合成平台
- 批准号:
571186-2021 - 财政年份:2021
- 资助金额:
$ 59.5万 - 项目类别:
Banting Postdoctoral Fellowships Tri-council
Lindau - Cobalt Catalysis as an Inexpensive, Earth-Abundant Platform for the Synthesis of Pharmaceuticals
Lindau - 钴催化作为一种廉价、地球资源丰富的药物合成平台
- 批准号:
571750-2021 - 财政年份:2021
- 资助金额:
$ 59.5万 - 项目类别:
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Construction of chiral quaternary carbon center using cobalt-photoredox catalysis and tertiary radicals
利用钴光氧化还原催化和叔自由基构建手性季碳中心
- 批准号:
20K15946 - 财政年份:2020
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CAS: Sustainable Technologies for Building Molecules: Cobalt, Nickel, and Copper Catalysis
CAS:构建分子的可持续技术:钴、镍和铜催化
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1956457 - 财政年份:2020
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Photoelectrochemically Driven Water-Oxidation Catalysis by Perylene Diimide Plus Cobalt-Oxide Based Photoanodes: Fundamental Studies En Route to Second-Generation Systems
苝二酰亚胺加氧化钴基光阳极的光电化学驱动水氧化催化:第二代系统的基础研究
- 批准号:
1664646 - 财政年份:2017
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Synthesis of New Iron and Cobalt Silyl Pincer Complexes for Applications in Catalysis
用于催化应用的新型铁钴甲硅烷基钳配合物的合成
- 批准号:
459159-2014 - 财政年份:2016
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Postgraduate Scholarships - Doctoral