SusChEM: Catalytic Activation of Small Molecules by Nickel and Iron Pincer Complexes

SusChEM：镍和铁钳配合物催化活化小分子

• 批准号: 1464734
• 负责人: Hairong Guan
• 金额: $ 42万
• 依托单位: University of Cincinnati Main Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1464734&HistoricalAwards=false
• 关键词: SusChEM; Catalytic; Activation; Small; Molecules

With this award, the Chemical Catalysis Program of the Chemistry Division is funding Professor Hairong Guan of the University of Cincinnati to design, synthesize and study catalysts using earth-abundant metals, such as nickel and iron. Such metals are inexpensive and display promise as the basis for the catalysis of chemical processes that are industrially and economically important. Examples include the conversion of a primary greenhouse gas, carbon dioxide, to liquid fuels, the replacement of toxic reagents in pharmaceutical synthesis, and the release of hydrogen from a hydrogen-storage chemicals. Professor Guan is also developing research-based materials for a laboratory course focusing on catalysis, and providing research opportunities to American Chemical Society Project SEED students as well as to students from groups that are underrepresented in STEM fields. In this project, Professor Guan is studying pincer-ligated nickel complexes as catalysts for the hydrogenation of carbon dioxide to methanol using dihydrogen and the cyanomethylation of aldimines and epoxides to beta-amino nitriles and gamma-hydroxy nitriles. Related iron pincer complexes are being developed to catalyze the dehydrogenation of ammonia-borane, which exhibits desirable properties as a chemical hydrogen-storage material. The mechanistic details of these catalytic processes including the kinetics and thermodynamics of the elemental steps are being studied so that more active and robust catalysts can be designed rationally. Other broader impacts of the project include the development of a research-based laboratory course and collaborations with a primarily undergraduate institution and local chemical companies.

有了这个奖项，化学系的化学催化项目资助辛辛那提大学的管海荣教授设计，合成和研究使用地球上丰富的金属，如镍和铁的催化剂。 这些金属价格低廉，并显示出作为工业和经济上重要的化学过程催化剂的基础的希望。 例子包括将主要温室气体二氧化碳转化为液体燃料，在药物合成中取代有毒试剂，以及从储氢化学品中释放氢。 关教授还为专注于催化的实验室课程开发基于研究的材料，并为美国化学学会项目SEED学生以及来自STEM领域代表性不足的群体的学生提供研究机会。 在这个项目中，管教授正在研究钳形连接镍配合物作为催化剂，用于使用二氢将二氧化碳氢化为甲醇，以及将醛亚胺和环氧化物氰甲基化为β-氨基腈和γ-羟基腈。 正在开发相关的铁钳络合物以催化氨-硼烷的脱氢，氨-硼烷表现出作为化学储氢材料的期望性能。 这些催化过程的机理细节，包括动力学和热力学的元素步骤正在研究，以便更积极和强大的催化剂可以合理地设计。 该项目的其他更广泛的影响包括以研究为基础的实验室课程的开发，以及与主要本科院校和当地化学公司的合作。