MRI: Acquisition of a Single-Crystal X-ray Diffractometer for Chemical Crystallography Research and Training

在主要研究仪器项目（MRI）和化学研究仪器项目（CRIF）的支持下，辛辛那提大学的William Connick教授和他的同事Anna Gudmundsdottir、Jeanette Krause、James Mack II和Hairong Guan获得了一个双源、微聚焦单晶x射线衍射仪，该衍射仪配备了光子探测器和低温装置。一般来说，x射线衍射仪可以精确测量分子的完整三维结构，包括键的距离和角度。它还提供了一个分子相对于邻近分子的空间排列的准确信息。这里描述的研究影响了许多领域，包括有机和无机化学，材料化学和生物化学。该仪器是该机构和区域合作者的化学和生物化学本科生和研究生的教学、研究和研究培训的一个组成部分。此外，该仪器使高中生和本科生接触到晶体学和研究。通过首席研究员参与ACS-Project SEED、Dreyfus、NSF-REU和女性参与科学与工程项目，代表性不足的群体的参与得到了加强。该奖项旨在加强各级的研究和教育，特别是在以下领域：(a)通过金属复合光化学识别有效的光过程，通过每个光子吸收释放两个电子来存储能量，(b)研究传感器材料，以确定材料对化学蒸汽和水离子的比色和基于发光的响应机制。(c)制备和表征化学转化和绿色技术的潜在催化剂；(d)表征释放针对特定底物或本身是代谢途径或纳米结构材料成分的活性物质的潜在化学性质。

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor William Connick from the University of Cincinnati and colleagues Anna Gudmundsdottir, Jeanette Krause, James Mack II and Hairong Guan have acquired a dual source, microfocus single crystal X-ray diffractometer equipped with a photon detector and a cryogenic device. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles. It also provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact a number of areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution and regional collaborators. Additionally, the instrument exposes high school and undergraduate students to crystallography and research. Participation of underrepresented groups is enhanced through the principal investigator's involvement with ACS-Project SEED, Dreyfus, NSF-REU and Women in Science and Engineering programs. The award is aimed at enhancing research and education at all levels, especially in areas such as (a) identifying efficient photoprocesses for storing energy via metal-complex photochemistry that releases two electrons per photon absorbed, (b) studying sensor materials to determine the mechanisms of colorimetric and luminescence-based responses of materials to chemical vapors and aqueous ions, (c) preparing and characterizing potential catalysts for chemical transformations and green technologies and (d) characterizing the underlying chemistry of agents that release reactive species that target specific substrates or are themselves components in metabolic pathways or nanostructured materials.