Human skin equivalent constructs: enhanced culturing and application of laboratory-grown skin through mathematical modelling and in silico experimentation.

人体皮肤等效结构：通过数学建模和计算机实验增强实验室生长皮肤的培养和应用。

• 批准号: DP0773230
• 负责人: Prof Graeme Pettet
• 金额: $ 16.03万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0773230
• 关键词: Human; skin; equivalent; constructs; enhanced

Laboratory-grown human skin equivalent constructs, given social and legislative imperatives, will be critical for advances in novel treatment protocol definitions for wound repair, dermatogical screening of pharmacueticals and fundamental studies of skin diseases. In silico studies undertaken in this project will make a significant contribution to the effectiveness of the application of human skin constructs, by delivering new and deeper insights into the interplay between dependent processes that regulate the behaviour of skin, in vivo or ex vivo. The models and the researchers associated with this project will drive innovative studies in medical science over the next decade.

鉴于社会和立法的需要，实验室培养的人类皮肤等效结构将对伤口修复的新治疗方案定义、药物的皮肤病学筛选和皮肤病基础研究的进展至关重要。