Inter-fragmentary movement in callus formation in the early phase of fracture healing

骨折愈合早期骨痂形成中的骨折块间运动

• 批准号: DP0988124
• 负责人: Prof Graeme Pettet
• 金额: $ 20.76万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0988124
• 关键词: Inter; fragmentary; movement; callus; formation

Computational models of the early phase of bone fracture healing can provide the means to characterise the biochemical factors that control this process, and subsequently influence successful healing outcomes, with or without surgical intervention. This unique approach, incorporating soft tissue and fixation device contributions to fracture healing, will ultimately provide a sound basis for clinical decision-making, implant design and future experimental studies. Facilitating treatment optimisation, the outcomes of this project will create opportunities to reduce healthcare costs, physical impairment, and productivity losses for the 150,000 Australian patients hospitalised annually with fractures.

骨折愈合早期阶段的计算模型可以提供一种方法，以确定控制这一过程的生化因素，并随后影响成功的愈合结果，有或没有手术干预。这种独特的方法结合了软组织和固定器械对骨折愈合的贡献，最终将为临床决策、植入物设计和未来的实验研究提供良好的基础。促进治疗优化，该项目的成果将为每年因骨折住院的150，000名澳大利亚患者创造机会，减少医疗费用，身体损伤和生产力损失。