Transduction of neuronal signals by brain macroglial cells: implications for neuronal function
Transduction of neuronal signals by brain macroglial cells: implications for neuronal function
批准号:
DP0770955
负责人:
Prof David Williams
金额:
$18.25万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
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英文摘要
Study of mechanisms regulating brain cell (neuron and glial) communication is essential for understanding of normal brain function and transformations that occur in neurodegenerative states and age-related disorders. Mechanisms underlying neuron-glia communication are not well understood. By combining cell physiology, digital imaging technologies, and genetically designed and delivered molecules we will enhance our understanding of this brain cell communication and critical roles played by intracellular calcium. This will enhance international competitiveness of Australian biological research and provide novel insight of glial function in neurodegeneration and potential for specific therapeutic intervention in disease.
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