Mimicking peptide structure - towards an aqueous environment

模仿肽结构 - 针对水环境

• 批准号: DP0771901
• 负责人: Prof Andrew Abell
• 金额: $ 20.82万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0771901
• 关键词: Mimicking; peptide; structure; towards; aqueous

In this proposal we develop a fundamental understanding of the balance between 'weak' and 'strong' forces to define the properties of peptides and proteins. This will allow the design of new biological probes and materials with tailor-made chemical and physical properties for use in bioengineering, biotechnology, proteomics, and drug design. One such example is the design and preparation of a new chemical agent for the non-surgical treatment for cataract, the major cause of blindness world-wide.

在这项建议中，我们发展了对“弱”和“强”力之间的平衡的基本理解，以定义多肽和蛋白质的性质。这将允许设计新的生物探针和材料，具有定制的化学和物理特性，用于生物工程、生物技术、蛋白质组学和药物设计。其中一个例子是设计和制备了一种新的化学制剂，用于非手术治疗白内障，这是全世界失明的主要原因。