New separation technologies for profiling metabolites in biological samples

用于分析生物样品中代谢物的新分离技术

• 批准号: DP0771893
• 负责人: Prof Robert Shellie
• 金额: $ 10.36万
• 依托单位: University of Tasmania
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0771893
• 关键词: New; separation; technologies; profiling; metabolites

Metabolomics is an important new field of science that is contributing to the understanding of life processes at the molecular level. But a widely acknowledged major limitation of current metabolomics technologies is the inability to accurately identify high numbers of detected metabolites in the biological extracts being studied. This project will develop cutting-edge separation science approaches to address this existing problem in metabolomics analysis. In doing so it will provide enormous benefit to Australian biotechnology and biomedical research and play a major role in transferring capabilities to laboratories and research institutes that are involved in research aimed at elucidating biological pathways and networks.

代谢组学是一个重要的新科学领域，有助于在分子水平上理解生命过程。但是，目前代谢组学技术的一个广泛承认的主要限制是无法准确地识别正在研究的生物提取物中检测到的大量代谢物。该项目将开发尖端的分离科学方法，以解决代谢组学分析中存在的这一问题。这样做将为澳大利亚生物技术和生物医学研究带来巨大利益，并在向参与旨在阐明生物途径和网络的研究的实验室和研究机构转让能力方面发挥重要作用。