The sponge genome project and the evolution of multicellularity: using comparative genomics and developmental biology to reconstruct the first animals

海绵基因组计划和多细胞进化：利用比较基因组学和发育生物学重建第一批动物

• 批准号: DP0772241
• 负责人: Prof Bernard Degnan
• 金额: $ 23.93万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0772241
• 关键词: sponge; genome; project; evolution; multicellularity

Recently the entire genome from a living fossil - a sponge from the Great Barrier Reef - was sequenced (jointly supported by the ARC and US Department of Energy). As this genome is assembled and analysed, many of the fundamental biological processes that underlie the construction and evolution of all animals, including humans, will be revealed. In addition, sponge genomics will fuel innovations in medicine and biotechnology. Specifically, sponges are renowned for their capacity to synthesise bioactive compounds used in drug development, and high-grade silica used for semi-conductor construction. This project will identify the gene networks controlling these biosynthetic processes.

最近，来自活化石的整个基因组-大堡礁的海绵-被测序（由ARC和美国能源部联合支持）。随着这一基因组的组装和分析，包括人类在内的所有动物的构建和进化所依据的许多基本生物过程将被揭示。 此外，海绵基因组学将推动医学和生物技术的创新。 具体来说，海绵以其合成用于药物开发的生物活性化合物的能力以及用于半导体结构的高级二氧化硅而闻名。该项目将确定控制这些生物合成过程的基因网络。