Fast and high-resolution imaging of leukocyte trafficking using spinning-disk confocal microscopy (Z03)

使用转盘共聚焦显微镜对白细胞运输进行快速、高分辨率成像 (Z03)

• 批准号: 277853461
• 金额: --
• 依托单位: Walter-Brendel-Zentrum für experimentelle Medizin
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/277853461?language=en
• 关键词: Fast; resolution; imaging; leukocyte; trafficking

Using the technical service platform spinning-disk confocal microscopy (SDCM), we could significantly enhance the scientific spectrum of CRC 914 during the second funding period. We established cutting edge imaging applications to analyze fast processes during leukocyte trafficking in vitro, ex vivo and in vivo at high spatiotemporal resolution. For the third funding period, we will further expand our in vitro and in vivo imaging repertoire. This will help many projects within our CRC to gain new insights into the molecular mechanisms of leukocyte trafficking. Our SDCM platform will therefore be an essential component for the success of CRC 914 during the third funding period.

利用旋转圆盘共聚焦显微镜（SDCM）技术服务平台，我们可以在第二个资助期内显著增强CRC 914的科学谱。我们建立了尖端的成像应用程序，以高时空分辨率分析白细胞在体外、离体和体内运输过程中的快速过程。在第三个资助期，我们将进一步扩大我们的体外和体内成像系统。这将有助于我们CRC中的许多项目获得对白细胞运输的分子机制的新见解。因此，我们的SDCM平台将成为CRC 914在第三个资助期内取得成功的重要组成部分。