The Genomic Dimensionality of the Response to Natural Selection

自然选择反应的基因组维度

• 批准号: DP0769995
• 负责人: Prof Mark Blows
• 金额: $ 16.66万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2011-06-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0769995
• 关键词: Genomic; Dimensionality; Response; Natural; Selection

Many future advances in agriculture and medicine, as well as an understanding of adaptive evolution in natural and pest populations will require discovering the genes that regulate the expression of complex traits. Microarray technology is at the forefront of modern genomics, but despite its promise, is currently restricted in its utility by significant analytical problems associated with the analysis of the large number of gene expression profiles and their interpretation. Analytical approaches will be developed that will substantially enhance the ability of transcriptional profiling to effectively uncover key genes underlying important phenotypes of interest across the biological and medical sciences.

未来农业和医学的许多进步，以及对自然和害虫种群适应性进化的理解，都需要发现调控复杂性状表达的基因。微阵列技术处于现代基因组学的最前沿，但是尽管其前景广阔，但目前其实用性受到与大量基因表达谱的分析及其解释相关的重大分析问题的限制。 将开发分析方法，这将大大提高转录谱的能力，以有效地揭示关键基因的重要表型的利益在整个生物和医学科学。