Why does the genetic nearly-null subspace exist?

该项目旨在通过同时测量这些几乎为零的子空间中新的突变方差的输入以及作用于这些新突变的选择来确定为什么存在几乎为零的遗传子空间，从而导致观察到的低水平的遗传方差。生物为应对人类干扰、迁移到新环境或气候变化而进化的能力是由遗传变异的可用性决定的。多元遗传分析的最新进展表明，由数量性状描述的表型的很大一部分与之相关的遗传变异很少，因此将倾向于受到进化限制

This project aims to determine why nearly-null genetic subspaces exist by simultaneously measuring the input of new mutational variance in these nearly-null subspaces and the selection that acts on these new mutations to result in the observed low levels of standing genetic variance. The ability of organisms to evolve in response to human disturbance, translocation to new environments, or climate variation is governed by the availability of genetic variation. Recent advances in multivariate genetic analysis have demonstrated that a substantial proportion of a phenotype described by quantitative traits has very little genetic variance associated with it, and will therefore tend to be subjected to evolutionary limits