Transport von CLAVATA Rezeptoren und Signalmodifikatoren zwischen Membranen (B04)

植物细胞表达大量的膜定位受体样激酶（RLKs），它们可以识别来自细胞质或病原体的扩散信号。我们的长期目标是了解不同RLKs的相互作用如何解码肽配体信号进入高度特异性的细胞反应。作为一个范例，我们将在这里研究控制植物干细胞生态位的CLV信号通路中RLKs的复合物、膜间运输和周转，并研究在拟南芥中直接作用于下游的膜相关异三聚体g蛋白和细胞质激酶的相互作用。

Plant cells express a bewildering number of membrane localised receptor-like kinases (RLKs) that recognise diffusible signals from the apoplasm or from pathogens. Our long-term goal is to understand how the interplay of diverse RLKs can decode peptide ligand signalling into highly specific cellular responses. As a paradigm, we will here investigate the complexes, intermembrane transport and turnover of RLKs in the CLV signalling pathway that control the plant stem cell niches, and study interacting membrane-associated heterotrimeric G-proteins and cytoplasmic kinases that act immediately downstream in Arabidopsis thaliana.