Modulation of priming TBS with NMES on neuroplasticity and clinical rehabilitation effects on focal hand dystonia

用 NMES 调节启动 TBS 对局灶性手肌张力障碍的神经可塑性和临床康复效果

• 批准号: 21J10563
• 负责人: 曹 娜
• 金额: $ 0.96万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for JSPS Fellows
• 财政年份: 2021
• 资助国家: 日本
• 起止时间: 2021-04-28 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21J10563/
• 关键词: Theta burst stimulation; Neuroplasticity; NMES; Dose effect; Concurrent; Plasticity; Priming

Two studies have been completed this year. The first study, which associate cortical and peripheral stimulations concurrently, has been published in thejournal Neuroscience Letters and aslo been shared in the international conference whcih been held in San Diego. The second study, the dose effect of the concurrent and associative electrical stimulation, which itspreliminary results has been presented in the conference “International Functional Electrical Stimulation Society (IFESS) RehabWeek” last year, has been completed and finished the manuscript this year and will be submitted to the international journal soon. All the project will lead to the development of new neuromodulation method that uses non-invasive brain stimaltions to achieve a better neuroplasticity.

今年完成了两项研究。第一项同时关联皮层和外周刺激的研究已发表在《神经科学快报》杂志上，并在圣地亚哥举行的国际会议上分享。第二项研究，同时和联合电刺激的剂量效应，其初步结果已在去年的“国际功能性电刺激协会（IFESS）RehabWeek”会议上发表，今年已完成并完成手稿，即将提交给国际期刊。所有的项目将导致新的神经调节方法的发展，使用非侵入性的大脑刺激，以实现更好的神经可塑性。

项目成果

Short-term facilitation effects elicited by cortical priming through theta burst stimulation and functional electrical stimulation of upper-limb muscles

通过上肢肌肉的θ爆发刺激和功能性电刺激皮质启动引起的短期促进效应

• DOI: 10.1007/s00221-022-06353-3
• 发表时间: 2022
• 期刊: Experimental Brain Research
• 影响因子: 2
• 作者: Cao Na;Sasaki Atsushi;Yuasa Akiko;Popovic Milos R.;Milosevic Matija;Nakazawa Kimitaka
• 通讯作者: Nakazawa Kimitaka

Longer duration cortical and peripheral stimulation may enhance corticospinal facilitation

持续时间较长的皮质和外周刺激可能会增强皮质脊髓促进作用

• 发表时间: 2022
• 作者: Araya Kibrom Desta;Shuji Ohira;Ismail Arai;Kazutoshi Fujikawa;Na Cao
• 通讯作者: Na Cao

Effective corticospinal excitability neuromodulation elicited by short-duration concurrent and synchronized associative cortical and neuromuscular stimulations

短时并发和同步关联皮质和神经肌肉刺激引起有效的皮质脊髓兴奋性神经调节

• DOI: 10.1016/j.neulet.2022.136910
• 发表时间: 2022
• 期刊: Neuroscience Letters
• 影响因子: 2.5
• 作者: Cao Na;Sasaki Atsushi;Yuasa Akiko;Popovic Milos R.;Milosevic Matija;Nakazawa Kimitaka
• 通讯作者: Nakazawa Kimitaka

Simultaneous but not delayed repetitive paired cortical and neuromuscular electrical stimulations effectively facilitate corticospinal excitability

同时但不延迟重复配对皮质和神经肌肉电刺激可有效促进皮质脊髓兴奋性

• 发表时间: 2022
• 作者: Araya Kibrom Desta;Shuji Ohira;Ismail Arai;Kazutoshi Fujikawa;Satomi Ohtsuka;Taisei Okumura;Yuna Τabuchi;Tomoyuki Miyagawa;Naoki Kanayama;Masaki Magari;Naoya Hatano;Hiroyuki Sakagami;Futoshi Suizu;Teruhiko Ishikawa;Hiroshi Tokumitsu;Na Cao
• 通讯作者: Na Cao