Molecular Investigations into Polyglutamine Repeat Proteins

聚谷氨酰胺重复蛋白的分子研究

• 批准号: DP0773627
• 负责人: Prof Stephen Bottomley
• 金额: $ 20.8万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-02 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0773627
• 关键词: Molecular; Investigations; into; Polyglutamine; Repeat

The proposed research program, will provide significant fundamental insight into the processes that control protein aggregation and disease. Investigating processes central to protein aggregation is important, as it will further our understanding of these critically-important events and our understanding of disease processes. Such knowledge will increase Australia's international research standing, as well as having the potential to generate novel therapies, that prevent neurodegeneration.

拟议的研究计划将为控制蛋白质聚集和疾病的过程提供重要的基本见解。 研究蛋白质聚集的核心过程是重要的，因为它将进一步加深我们对这些至关重要的事件的理解，以及我们对疾病过程的理解。 这些知识将提高澳大利亚的国际研究地位，并有可能产生新的治疗方法，防止神经变性。