Rolled-up metal/dielectric hybrid structures as on-chip integrative resonator devices for multifunctional optical label-free detection

光学无标记传感器是生物化学中一种强大的分析工具，片上集成光学无标记传感器的实现将促进许多应用的传感过程。最近，混合光子-等离子体结构已经被研究用于光学无标记传感，其具有比纯光子或等离子体结构更好的性能。最近，我们研究了一种基于卷起纳米技术的电介质/金属混合结构。提出了一种新的光子-等离子体混合模式，该模式将光子和等离子体分量沿卷起的管状结构的圆周沿着耦合。以这种方式，通过例如改变管壁中的金属层的比例，用于高性能无标记传感器的光子-等离子体混合模式的优化变得可能。此外，受卷起的纳米技术的青睐，混合光学结构的片上单片集成变得非常可行。因此，该提案的主要目标是进一步研究和优化基于卷起的纳米技术的光子-等离子体激元混合环形谐振器。它依赖于理解导致混合光学模式产生的机制，这将在项目开始时进行全面研究。在此基础上，设计并优化了光子-等离子体激元混合谐振腔，并进行了无标记传感实验。基于我们建立的方法，结合实验室芯片制造和卷起的纳米技术，高灵敏度和芯片上集成的光流体无标记传感器将在本项目结束时实现。

Optical label-free sensing is a powerful analysis tool in biochemistry, and implementation of on-chip integrative optical label-free sensors will boost the sensing process for many applications. Recently, hybrid photonic-plasmonic structures have been investigated for optical label-free sensing with a better performance than that of pure photonic or plasmonic structures. Very recently, we investigated a dielectric/metal hybrid structure based on rolled-up nanotechnology. A new kind of photonic-plasmonic hybrid mode which couples the photonic and plasmonic components along the circumference of the rolled-up tubular structure is demonstrated. In this manner, optimization of photonic-plasmonic hybrid modes for high performance label-free sensors becomes possible by for instance varying the proportion of the metal layer in the tube wall. In addition, favoured by rolled-up nanotechnology, the on-chip monolithic integration of hybrid optical structures becomes well-feasible. Therefore, the main objective of the proposal is to further investigate and optimize photonic-plasmonic hybrid ring resonators based on rolled-up nanotechnology. It relies on understanding the mechanisms leading to the generation of the hybrid optical modes, which will be fully investigated at the beginning of the project. After that, a photonic-plasmonic hybrid resonator will be designed and optimized, and label-free sensing experiments will be performed. Based on our established methodology combining lab-on-a-chip fabrication and rolled-up nanotechnology, highly sensitive and on-chip integrative optofluidic label-free sensors will be realized by the end of this project.