Development of Pulse Acquisition System for Accurate Beam Quality Measurement of Multi-ion Therapy and for Accurate Prediction of Biological effect

开发脉冲采集系统,用于多离子治疗的精确束流质量测量和生物效应的准确预测

基本信息

  • 批准号:
    20K16776
  • 负责人:
  • 金额:
    $ 2.5万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
  • 财政年份:
    2020
  • 资助国家:
    日本
  • 起止时间:
    2020-04-01 至 2024-03-31
  • 项目状态:
    已结题

项目摘要

This study aims to accurately measure the beam quality of carbon ions using a microdosimeter in carbon ion therapy. In the MCA currently used to measure the energy spectrum according to the magnitude of the measured pulse signal, it has been confirmed that the signal in the low energy region is unstable, so we try to directly acquire the pulse and directly process the signal without using the MCA. This work will include filtering accompanied by noise rejection using Fourier transforms for signal processing. Through securing a more accurate energy spectrum, we intend to contribute to the treatment of cancer patients by more accurately measuring the quality of the beam of carbon ion therapy.
本研究旨在使用碳离子治疗中的微剂量计准确测量碳离子的束质量。目前采用的根据被测脉冲信号大小来测量能谱的MCA中,已经证实低能区信号不稳定,因此我们尝试不使用MCA直接采集脉冲并直接处理信号。这项工作将包括使用傅里叶变换进行信号处理并伴有噪声抑制的滤波。通过确保更准确的能谱,我们打算通过更准确地测量碳离子治疗束的质量来为癌症患者的治疗做出贡献。

项目成果

期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
University of Wollongong/Centre for Medical Radiation Physics(オーストラリア)
卧龙岗大学/医学辐射物理中心(澳大利亚)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Predicting the Biological Effects of Human Salivary Gland Tumour Cells for Scanned 4He-, 12C-, 16O-, and 20Ne-Ion Beams Using an SOI Microdosimeter
使用 SOI 微剂量计预测 4He、12C、16O 和 20Ne 离子束扫描对人唾液腺肿瘤细胞的生物学效应
  • DOI:
    10.3390/app12126148
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Lee Sung Hyun;Mizushima Kota;Yonai Shunsuke;Matsumoto Shinnosuke;Mizuno Hideyuki;Nakaji Taku;Kohno Ryosuke;Iwata Yoshiyuki;Shirai Toshiyuki;Pan Vladimir;Kok Angela;Povoli Marco;Tran Linh T.;Rosenfeld Anatoly B.;Suzuki Masao;Inaniwa Taku
  • 通讯作者:
    Inaniwa Taku
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LEE SUNGHYUN其他文献

LEE SUNGHYUN的其他文献

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{{ truncateString('LEE SUNGHYUN', 18)}}的其他基金

Development of dose measurement system for therapeutic carbon-ion beam using a glass block without quenching effect
开发使用无淬火效应的玻璃块的治疗碳离子束剂量测量系统
  • 批准号:
    23K14859
  • 财政年份:
    2023
  • 资助金额:
    $ 2.5万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists

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使用双体模技术提高硼中子俘获治疗照射场剂量和束质量估计的准确性
  • 批准号:
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  • 批准号:
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  • 财政年份:
    2013
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  • 批准号:
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  • 财政年份:
    2013
  • 资助金额:
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Feasibility of using ion implantation to improve the efficiency and beam quality of micro-pixelated linear arrays for maskless lithography
使用离子注入提高无掩模光刻微像素化线性阵列效率和光束质量的可行性
  • 批准号:
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  • 财政年份:
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Monte Carlo calculations and experimental determination of beam quality conversion factors for the calibration of high-energy radiotherapy sources
高能放射治疗源校准中光束质量转换因子的蒙特卡罗计算和实验确定
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  • 财政年份:
    2012
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    $ 2.5万
  • 项目类别:
    Alexander Graham Bell Canada Graduate Scholarships - Doctoral
Monte Carlo calculations and experimental determination of beam quality conversion factors for the calibration of high-energy radiotherapy sources
高能放射治疗源校准中光束质量转换因子的蒙特卡罗计算和实验确定
  • 批准号:
    410216-2011
  • 财政年份:
    2011
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    $ 2.5万
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Beam Quality Determination of Ultra High Energy Neutrons
超高能中子的束流质量测定
  • 批准号:
    63480248
  • 财政年份:
    1988
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    $ 2.5万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (B)
High-, moderate- and low-LET ion beams for treatment of radioresistant tumors: Impact of beam quality, tumor grading and hypoxic status on radiation response
高、中、低 LET 离子束用于治疗放射抗性肿瘤:光束质量、肿瘤分级和缺氧状态对放射反应的影响
  • 批准号:
    319589509
  • 财政年份:
  • 资助金额:
    $ 2.5万
  • 项目类别:
    Research Grants
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