A National Biomedical Electron Paramagnetic Resonance and Molecular Imaging Centre

国家生物医学电子顺磁共振与分子影像中心

• 批准号: LE0775660
• 负责人: Prof Harald Schmidt
• 金额: $ 33.34万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-09-20 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0775660
• 关键词: National; Biomedical; Electron; Paramagnetic; Resonance

Multifrequency continuous wave and pulsed electron paramagnetic resonance spectroscopy and molecular imaging instrumentation will provide forefront technologies in identifying, characterising, quantifying, visualising and manipulating fundamental chemical and biologically relevant processes involving free radicals, metalloproteins and metal ions. This technology is crucial in validating these functional processes at the cellular and tissue level and for providing invaluable and unique biomedical information under physiological conditions. This synergistic and highly integrative approach will make available new techniques for identifying major disease mechanisms such as cardiovascular disease with a potential to improve and maintain health.

多频连续波和脉冲电子顺磁共振波谱和分子成像仪器将在识别、表征、量化、可视化和操纵涉及自由基、金属蛋白和金属离子的基本化学和生物相关过程方面提供前沿技术。这项技术对于在细胞和组织水平上验证这些功能过程以及在生理条件下提供无价和独特的生物医学信息至关重要。这一协同和高度综合的方法将提供新的技术，用于确定有可能改善和维持健康的主要疾病机制，如心血管疾病。