Functional elucidation of plasmacytoid dendritic cell-regulatory T cell linkage regulated by fatty acid binding proteins

脂肪酸结合蛋白调节的浆细胞样树突状细胞-调节性T细胞连接的功能阐明

• 批准号: 20K19632
• 负责人: Kobayashi Shuhei
• 金额: $ 2.75万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K19632/
• 关键词: FABP; pDC; Treg; lipid metabolism; FABP5; Tumor microenvironment; Lipid metabolism; Tumor Immunology; 脂質応答; 免疫制御

项目成果

Fatty acid‐binding protein 5 limits the generation of Foxp3+ regulatory T cells through regulating plasmacytoid dendritic cell function in the tumor microenvironment

• DOI: 10.1002/ijc.33777
• 发表时间: 2021-08
• 期刊: International Journal of Cancer
• 影响因子: 6.4
• 作者: Shuhei Kobayashi;Tunyanat Wannakul;Kaname Sekino;Yu Takahashi;Yoshiteru Kagawa;Hirofumi Miyazaki;Banlanjo Umaru;Shuhan Yang;Yui Yamamoto;Y. Owada

Fatty acid-binding protein 3 controls contact hypersensitivity through regulating skin dermal Vγ4+ γ/δ T cell development.

脂肪酸结合蛋白 3 通过调节皮肤真皮 Vγ4+ γ/δ T 细胞发育来控制接触超敏反应。

• 发表时间: 2021
• 作者: Shuhei Kobayashi;Yoshiteru Kagawa;Hirofumi Miyazaki;Yuji Owada
• 通讯作者: Yuji Owada

Fatty acid-binding protein 5 limits ILC2-mediated allergic lung inflammation in a murine asthma model.

• DOI: 10.1038/s41598-020-73935-y
• 发表时间: 2020-10-06
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Kobayashi S;Tayama S;Phung HT;Kagawa Y;Miyazaki H;Takahashi Y;Maruyama T;Ishii N;Owada Y
• 通讯作者: Owada Y