Therapeutic polymer nanoreactor with site-specific activation of targeting Warburg metabolism for metastatic breast cancer treatment

具有靶向 Warburg 代谢位点特异性激活的治疗性聚合物纳米反应器用于转移性乳腺癌治疗

• 批准号: 20K20209
• 负责人: LI JUNJIE
• 金额: $ 2.5万
• 依托单位: Kyushu University (2022)Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine (2020-2021)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K20209/
• 关键词: Immunotherapy; Nanoreactors; Pyroptosis; Self-assembly; Vesicles; Tumor metabolism; immunotherapy; nanoreactors; pyroptosis; self-assembly; vesicles; tumor metabolism; vesicle; nanoreactor; drug delivery

项目成果

Hypoxia-responsive block copolymer polyprodrugs for complementary photodynamic-chemotherapy

用于补充光动力化疗的缺氧响应性嵌段共聚物聚前药

• DOI: 10.1016/j.jconrel.2021.09.023
• 发表时间: 2021
• 期刊: Journal of Controlled Release
• 影响因子: 10.8
• 作者: Qinghao Zhou;Fathelrahman Mohammed;Yuheng Wang;Jingbo Wang;Nannan Lu;Junjie Li;Zhishen Ge
• 通讯作者: Zhishen Ge

Glucose oxidase (GOD) as cancer therapeutics―GOD of Small Things

葡萄糖氧化酶（GOD）作为癌症疗法——小事物的GOD

• 发表时间: 2022
• 作者: Robin Rajan;Nishant Kumar;Kazuaki Matsumura;Junjie Li
• 通讯作者: Junjie Li

Non-fouling or super-stealth vesicle

无污染或超隐形囊泡

• 发表时间: 2022

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

• DOI: 10.1021/jacs.0c09029
• 发表时间: 2021-01-20
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Li, Junjie;Kataoka, Kazunori
• 通讯作者: Kataoka, Kazunori

Strategies to advance functionality of polymeric nanomedicine

提高聚合物纳米医学功能的策略

• 发表时间: 2022
• 作者: Alisha Debas;Robin Rajan;Kazuaki Matsumura;Junjie Li
• 通讯作者: Junjie Li