Role of heme for plastid retrograde signaling (C04)

血红素在质体逆行信号传导中的作用 (C04)

• 批准号: 317556048
• 金额: --
• 依托单位: Arbeitsgruppe Pflanzenphysiologie
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2023-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/317556048?language=en
• 关键词: Role; heme; plastid; retrograde; signaling

Adverse environmental conditions induce acclimation responses, which are communicated through chloroplasts to adjust nuclear gene expression. Following the concept of plastid-derived retrograde signaling, ferrochelatase 1 (FC1) and its catalyzed product heme are proposed as appropriate components of tetrapyrrole-derived retrograde signaling. It is aimed to explore the role of these components in signal transduction during stress acclimation. The search for FC1-interaction partners including heme-transporters is intended to identify further components and to substantiate the proof of heme-mediated retrograde signaling.

不利的环境条件诱导驯化反应，这是通过叶绿体沟通，以调整核基因的表达。根据质体来源的逆行信号传导的概念，铁螯合酶1（FC 1）及其催化产物血红素被认为是四吡咯来源的逆行信号传导的合适组分。目的是探讨这些组分在胁迫适应过程中的信号转导作用。搜索FC1相互作用的合作伙伴，包括血红素转运蛋白的目的是确定进一步的组件，并证实血红素介导的逆行信号的证据。