Electron-collision induced fragmentation and intermolecular energy transfer processes in water and hydrated biomolecule clusters studied with multi-particle coincidence experiments

通过多粒子符合实验研究水和水合生物分子簇中电子碰撞诱导的碎裂和分子间能量转移过程

• 批准号: 328557844
• 负责人: Dr. Xueguang Ren, Ph.D.
• 金额: --
• 依托单位: Physikalisch-Technische Bundesanstalt (PTB)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/328557844?language=en
• 关键词: Electron; collision; induced; fragmentation; intermolecular

This project aims to explore low-energy electron impact-induced molecular ionization, fragmentation and intermolecular energy transfer which are reactions relevant in radiation damage of DNA. One central point is to explore the presumably strong influence of a natural environment like attached water molecules on the break-up of bio-molecules (BM). Here of particular interest will be the intermolecular Coulombic decay (ICD) and related energy and charge transfer processes in molecular clusters which in relation with BM are essentially unexplored. E.g., energy transfer from water to the BM on one hand can enhance fragmentation and on the other hand fast energy transfer in the reverse direction can quench fragmentation. First experiments will be performed on tetrahydrofuran (THF) the simplest molecular analog of deoxyribose in the DNA backbone. A multi-particle imaging spectrometer with an implemented low energy electron beam and a heatable supersonic molecular jet target will be used. This worldwide singular experimental set-up is uniquely suited to study electron-driven break-up processes by efficiently measuring all the electrons and ions (their mass, charge, direction and energy). Triple- up to quintuple- coincidence experiments will be performed with high fragment ion mass resolution and high energy resolution.

该项目旨在探索低能电子冲击诱导的分子电离，碎片化和分子间的能量转移，这与DNA的辐射损伤相关。一个核心是探索自然环境（如附着的水分子）对生物分子（BM）分裂的强大影响。特别感兴趣的是分子间库仑衰减（ICD）以及分子簇中的相关能量和电荷转移过程，与BM相关，基本上未探索。例如，一方面，能量从水到BM可以增强碎片化，另一方面，在反向方向上的快速能量转移会消除碎片。第一个实验将在四氢呋喃（THF）上进行DNA主链中最简单的脱氧核糖分子类似物。将使用具有实现的低能电子束和可加热的超音速分子射流目标的多粒子成像光谱仪。通过有效测量所有电子和离子（它们的质量，电荷，方向和能量），这种全球奇异的实验设置非常适合研究电子驱动的分解过程。将使用高碎片离子质量分辨率和高能量分辨率进行三重至五重合的结合实验。

项目成果

Analysis of multiple scattering contributions in electron-impact ionization of molecular hydrogen

分子氢电子轰击电离中多重散射贡献的分析

• DOI: 10.1088/1361-6455/aa8b4a
• 发表时间: 2017
• 期刊: Journal of Physics B: Atomic, Molecular and Optical Physics
• 作者: Xueguang Ren;Khokon Hossen;Enliang Wang;M S Pindzola;Alexander Dorn;James Colgan
• 通讯作者: James Colgan

Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules

• DOI: 10.1038/s41567-018-0214-9
• 发表时间: 2018-07
• 期刊: Nature Physics
• 影响因子: 19.6
• 作者: X. Ren;Enliang Wang;A. D. Skitnevskaya;A. Trofimov;K. Gokhberg;A. Dorn

Two-center interference in electron-impact ionization of molecular hydrogen

氢分子电子轰击电离中的二中心干涉

• DOI: 10.1103/physreva.97.022706
• 发表时间: 2018
• 期刊: PHYSICAL REVIEW A
• 影响因子: 2.9
• 作者: Li Xingyu;Ren Xueguang;Hossen Khokon;Wang Enliang;Chen Xiangjun;Dorn Alex;er
• 通讯作者: er

An (e, 2e+ ion) study of electron-impact ionization and fragmentation of tetrafluoromethane at low energies

• DOI: 10.1140/epjd/e2017-80665-8
• 发表时间: 2018-03
• 期刊: The European Physical Journal D
• 作者: Khokon Hossen;X. Ren;Enliang Wang;S. Kumar;A. Dorn

Observation of fast and slow interatomic Coulombic decay in argon dimers induced by electron-impact ionization

• DOI: 10.1103/physreva.96.032715
• 发表时间: 2017-09
• 期刊: Physical Review A
• 影响因子: 2.9
• 作者: X. Ren;T. Miteva;P. Kolorenč;K. Gokhberg;A. Kuleff;L. Cederbaum;A. Dorn