Combinatorial control of gene expression by heterodimers of the group C/S1 bZIP transcription factor network

C/S1 bZIP 转录因子网络异二聚体对基因表达的组合控制

• 批准号: 33401371
• 负责人: Professor Dr. Wolfgang Dröge-Laser
• 金额: --
• 依托单位: Lehrstuhl für Pharmazeutische Biologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2007
• 资助国家: 德国
• 起止时间: 2006-12-31 至 2013-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/33401371?language=en
• 关键词: Combinatorial; control; gene; expression; heterodimers

In previous work we have defined bZIP53 as a crucial transcriptional regulator in seed maturation. Both bZIP1 and bZIP53 control metabolic reprogramming in leaves under energy deprivation induced by an extended night treatment or in roots in response to salt stress. This project aims at further characterising the impact of these bZIPs and their corresponding heterodimerisation partners on stress-regulated target genes, studying the Arabidopsis transcriptome and metabolome. Finally, the impact of SNF1 Related Protein Kinases (SnRKs) on bZIP mediated transcription will be analysed.

在以前的工作中，我们已经定义bZIP53作为一个关键的转录调节子在种子成熟。bZIP1和bZIP53控制代谢重编程叶下的能量剥夺诱导延长夜间处理或根响应盐胁迫。该项目旨在进一步表征这些bZIPs及其相应的异源二聚体对胁迫调节靶基因的影响，研究拟南芥转录组和代谢组。最后，将分析SNF1相关蛋白激酶（SnRKs）对bZIP介导的转录的影响。