Unitization and the creation of episodic memory: Semantic, spatial, and schematic encoding factor effects on associative recognition and its electrophysiological correlates in young and old adults and cortical lesion patients

情景记忆的统一和创建：语义、空间和图式编码因素对年轻人、老年人和皮质病变患者的联想识别及其电生理相关性的影响

• 批准号: 362870284
• 负责人: Professor Dr. Axel Mecklinger
• 金额: --
• 依托单位: Lehrstuhl für Experimentelle Neuropsychologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2017
• 资助国家: 德国
• 起止时间: 2016-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/362870284?language=en
• 关键词: Unitization; creation; episodic; memory; Semantic

The main goal of this research project is to explore the circumstances under which encoding manipulations that promote unitization support associative recognition in young and old adults, and in patients with impairments in recollection and associative remembering. We hypothesize that unitization provides an effective method of supporting associative memory, as unitization increases memory primarily by increasing familiarity, which is less affected by old age and brain lesions than recollection. We plan to identify the conditions under which unitization facilitates associative memory by exploring encoding factors (semantic and spatial relations between objects) and retrieval factors (context effects and associative priming) using behavioral and electrophysiological measures. As a second research goal we plan to directly compare the value of unitization for the amelioration of memory deficits in two populations characterized by recollection deficits (stroke patients and old adults), using the same experimental paradigm in both populations. In a final set of studies, we will investigate whether unitization may be engendered not only by the presence of focal semantic and spatial relations between objects, but also by the activation of preexisting semantic schema knowledge. An overarching goal is to identify conditions under which old adults benefit from unitization to ameliorate their associative memory deficit by compensatory familiarity-based remembering. In light of the aging population and the high relevance of learning arbitrary associations in a variety of educational contexts, a better understanding of the role of unitization for the formation of novel associative memories is of great theoretical and practical relevance.

本研究项目的主要目标是探讨在何种情况下，编码操作，促进单位化支持联想识别的年轻人和老年人，并在患者的回忆和联想记忆障碍。我们假设，单位化提供了一种有效的方法，支持联想记忆，单位化增加记忆主要是通过增加熟悉，这是受老年和大脑病变比回忆。 我们计划确定的条件下，单位化促进联想记忆，探索编码因素（对象之间的语义和空间关系）和检索因素（上下文效应和联想启动）使用行为和电生理措施。作为第二个研究目标，我们计划在两个人群中使用相同的实验范式，在两个人群中使用相同的实验范式，直接比较单元化对改善两个人群中记忆缺陷的价值，这两个人群的特征是回忆缺陷（中风患者和老年人）。在最后一组的研究中，我们将调查是否unitization可能产生不仅存在的焦点语义和对象之间的空间关系，但也通过激活预先存在的语义图式知识。一个总体目标是确定条件下，老年人受益于unitization，以改善他们的联想记忆不足的补偿性熟悉为基础的记忆。鉴于人口老龄化和在各种教育背景下学习任意联想的高度相关性，更好地理解单元化对形成新颖联想记忆的作用具有重要的理论和实践意义。