The cognitive control of long-term memory: Neural dynamics in space and time

长期记忆的认知控制：空间和时间的神经动力学

• 批准号: 72271008
• 负责人: Professor Dr. Axel Mecklinger
• 金额: --
• 依托单位: Lehrstuhl für Experimentelle Neuropsychologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2008
• 资助国家: 德国
• 起止时间: 2007-12-31 至 2013-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/72271008?language=en
• 关键词: cognitive; control; long; term; memory

It is generally assumed that long-term memory is mediated by control processes that guide memory retrieval in order to selectively recover information relevant for current tasks and goals. Controlled memory retrieval results from a dynamic interplay between the medial temporal lobe (MTL), the prefrontal cortex (PFC), and other cortical areas. Recent functional imaging, ERP and neuropsychological studies have started to disclose the subprocesses of controlled memory retrieval and their neural correlates. However, important issues concerning the dynamic interplay of the aforementioned brain systems accomplishing controlled memory retrieval are still unresolved. Using combined event-related potential (ERP) and EEG variables in addition to measures of interareal phase synchrony, the present proposal aims at examining retrieval orientations, i.e. the specific form of processing initiated by a retrieval cue, and their neural correlates. In detail we want to investigate factors contributing to the initiation and maintenance of retrieval orientations and the influence of these control processes on other components of memory retrieval.

一般认为，长时记忆是由控制过程调节的，这些控制过程引导记忆提取，以便有选择地恢复与当前任务和目标相关的信息。受控记忆提取是内侧颞叶(MTL)、前额叶(PFC)和其他皮质区域之间动态相互作用的结果。最近的功能成像、事件相关电位和神经心理学研究已经开始揭示受控记忆提取的子过程及其神经关联。然而，有关上述大脑系统实现受控记忆提取的动态相互作用的重要问题仍未得到解决。除了区域间相位同步的测量外，本方案还使用事件相关电位(ERP)和脑电变量的组合，旨在检查提取定向，即由提取线索发起的特定形式的加工，以及它们的神经关联。具体地说，我们想要研究影响提取定向启动和维持的因素，以及这些控制过程对记忆提取的其他成分的影响。