Three-dimensional Simulation of Trabecular Bone Remodelling

目前有近200万澳大利亚人患有骨质疏松症。 统计数据显示，25%的澳大利亚女性和17%的男性会发生骨质疏松性骨折。 骨质疏松症的费用为每年74亿美元;受影响的人数和费用预计将继续增加。 显然，骨质疏松症诊断、骨折风险评估和有效治疗的改进仍是迫切需要的。 拟议的项目旨在创建一个工具，用于了解骨质流失的机制和预测骨质疏松症治疗的效果。 它代表了对推进骨质疏松症研究和最终降低骨质疏松性骨折发生率所需的知识基础的坚实贡献。

Nearly 2 million Australians currently suffer from osteoporosis. Statistics indicate that 25% of Australian women and 17% of men will develop an osteoporotic fracture. The cost of osteoporosis is $7.4 billion per annum; the numbers of affected individuals and costs are expected to continue increasing. Clearly, improvements to osteoporosis diagnosis, fracture risk assessment, and effective treatments are still urgently needed. The proposed project aims to create a tool for understanding the mechanisms of bone loss and predicting the effects of osteoporosis therapies. It represents a solid contribution to the knowledge base necessary for advancing osteoporosis research and ultimately reducing the incidence of osteoporotic fracture.