Three-dimensional Simulation of Trabecular Bone Remodelling

小梁骨重塑的三维模拟

• 批准号: DP0663271
• 负责人: Prof Karen Reynolds
• 金额: $ 18.68万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-03-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0663271
• 关键词: Three; dimensional; Simulation; Trabecular; Bone

Nearly 2 million Australians currently suffer from osteoporosis. Statistics indicate that 25% of Australian women and 17% of men will develop an osteoporotic fracture. The cost of osteoporosis is $7.4 billion per annum; the numbers of affected individuals and costs are expected to continue increasing. Clearly, improvements to osteoporosis diagnosis, fracture risk assessment, and effective treatments are still urgently needed. The proposed project aims to create a tool for understanding the mechanisms of bone loss and predicting the effects of osteoporosis therapies. It represents a solid contribution to the knowledge base necessary for advancing osteoporosis research and ultimately reducing the incidence of osteoporotic fracture.

目前有近200万澳大利亚人患有骨质疏松症。统计数据显示，25%的澳大利亚女性和17%的男性会患上骨质疏松性骨折。骨质疏松症每年造成74亿美元的损失；受影响的人数和费用预计将继续增加。显然，仍迫切需要改进骨质疏松症的诊断、骨折风险评估和有效的治疗。拟议的项目旨在创建一种工具，用于了解骨丢失的机制和预测骨质疏松症治疗的效果。这是对推进骨质疏松症研究并最终减少骨质疏松性骨折发生率所必需的知识基础的坚实贡献。