Biochemical studies on longevity using multicellular microorganism

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Caenorhabditis elegans, about 1 mm-long round worms, is a model organism with genetic advantages and used for the studies on cell death and longevity. On the other hand, as the technologies such as in vitro protein synthesis and Mass spectrometry are innovatively advanced, it becomes important to understand the biochemical functions of proteins. In the present study, combined with genetics and biochemistry, we tried toexamine the reactions of protein arginine methylation related to longevity.