cryoimmunotherapy for malignant bone tumors

本研究的目的是肿瘤组织冷冻处理可能诱导抗肿瘤作用，并抑制肿瘤的复发和转移。我们已经治疗了25例恶性肿瘤患者，他们的标准治疗手术，化疗和放疗失败。然后我们开始体外树突状细胞免疫治疗，用混合了OK-432的冷冻肿瘤组织进行脉冲。30%的患者产生免疫反应。之后，我们计划采用液氮联合树突状细胞免疫治疗，以减少局部复发和转移。

The purpose of this study is that the cryotreatment of tumor tissue may induced anti tumor effect, and that suppressed tumor recurrence and metastases. We have treated 25 patients for malignant tumors who failed standard treatment of surgery, chemotherapy, and radiotherapy. Then we started dendritic cell immunotherapy generated extra vivo, which pulsed with cryotreated tumor tissue mixed with OK-432. 3o% of patients induced immunological reactions. After that, we planed that the patients treated by cry treatment using liquid nitrogen combined with dendritic cell immunotherapy to reduce local recurrence and metastasis.