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A metabolic futile cycle is operating in gas gland cells of the swimbladder.

A metabolic futile cycle is operating in gas gland cells of the swimbladder.
鳔的气腺细胞中正在进行代谢无效循环。
批准号:
24657085
负责人:
HIROSE Shigehisa
金额:
$2.5万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012 至 --

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中文摘要
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英文摘要
H+/monocarboxylate transporters MCT1b and MCT4b were found to be highly expressed in the fugu swimbladder. Immunohistochemical analyses of metabolic enzymes demonstrated that a gluconeogenesis enzyme fructose-1,6-bisphosphatase (Fbp1) and a glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (Gapdh) are highly expressed in gas gland cells. The simultaneous catalyses of glycolysis and gluconeogenesis reactions suggest the presence of a futile cycle in gas gland cells to maintain the levels of ATP low and to generate heat that helps reduce the solubility of O2
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Histological demonstration of glucose transporters, fructose-1, 6-bisphosphatase, and glycogen in gas gland cells of the swimbladder : is a metabolic futile cycle operating
鱼鳔气腺细胞中葡萄糖转运蛋白、果糖-1、6-双磷酸酶和糖原的组织学证明:是一个代谢无效循环运行
DOI: 10.1016/j.bbrc.2011.12.006
发表时间: 2012
期刊: Biochem Biophys Res Commun
影响因子: --
作者: [Munakata K, Ookata K, Doi H, Baba O, Terashima T, Hirose S, Kato A.]
通讯作者: Kato A.
Visualization and characterization of GM2-rich lipid raft microdomain
  • 批准号:
    22657029
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.15万
  • 财政年份:
    2010
  • 负责人:
    HIROSE Shigehisa
  • 依托单位:
Identification of transporters involved in excretion of toxic sulfate and borate by seawater fish
  • 批准号:
    22370029
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.81万
  • 财政年份:
    2010
  • 负责人:
    HIROSE Shigehisa
  • 依托单位:
Molecular characterization of chloride cells and their mechanism of differentiation
  • 批准号:
    14104002
  • 项目类别:
    Grant-in-Aid for Scientific Research (S)
  • 资助金额:
    $72.55万
  • 财政年份:
    2002
  • 负责人:
    HIROSE Shigehisa
  • 依托单位:
Comparative molecular biology of the natriuretic peptide system (Molecular dissection and mechanism of differentiation of chloride cells)
  • 批准号:
    09102008
  • 项目类别:
    Grant-in-Aid for Specially Promoted Research
  • 资助金额:
    $100.86万
  • 财政年份:
    1997
  • 负责人:
    HIROSE Shigehisa
  • 依托单位:
海外基金