Identification of transporters involved in excretion of toxic sulfate and borate by seawater fish
Identification of transporters involved in excretion of toxic sulfate and borate by seawater fish
批准号:
22370029
负责人:
HIROSE Shigehisa
金额:
$11.81万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Sulfate and borate are abundant anion in seawater (SW), and excretion of excess sulfate and borate from ingested SW is essential for marine fish to survive because they are toxic. Marine teleosts excrete sulfate and borate via the urine produced in the kidney. The transporters that secrete and concentrate sulfate and borate in the urine have not previously been identified. Here, we have identified and characterized candidates for the long-sought transporters by using euryhaline pufferfish mefugu.
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DOI:
10.1242/jeb.044719
发表时间:
2010-09-15
期刊:
JOURNAL OF EXPERIMENTAL BIOLOGY
影响因子:
2.8
作者:
[Nawata, C. Michele, Hirose, Shigehisa, Kato, Akira]
通讯作者:
Kato, Akira
DOI:
10.1007/s10228-009-0150-x
发表时间:
2010-02
期刊:
Ichthyological Research
影响因子:
1.2
作者:
[A. Kato;Y. Maeno;S. Hirose]
通讯作者:
A. Kato;Y. Maeno;S. Hirose
Rhesus glycoprotein p2(Rhp2) is a novel member of the Rh family of ammonia transporters highly expressed in shark kidney
恒河猴糖蛋白 p2(Rhp2) 是氨转运蛋白 Rh 家族的新成员,在鲨鱼肾中高表达
DOI:
10.1074/jbc.m109.052068
发表时间:
2010
期刊:
J. Biol. Chem
影响因子:
--
作者:
[Nakada, T., Westhoff, C. M., Yamaguchi, Y., Hyodo, S., Li, X., Muro, T., Kato, A., Nakamura, N., Hirose, S.]
通讯作者:
S.
DOI:
10.3389/fphys.2010.00129
发表时间:
2010-01-01
期刊:
FRONTIERS IN PHYSIOLOGY
影响因子:
4
作者:
[Saito, Kaori, Nakamura, Nobuhiro, Hirose, Shigehisa]
通讯作者:
Hirose, Shigehisa
DOI:
10.1152/ajpregu.00417.2012
发表时间:
2013-05
期刊:
American journal of physiology. Regulatory, integrative and comparative physiology
影响因子:
--
作者:
[Shanshan Li;A. Kato;S. Takabe;Anping Chen;M. Romero;Takahiro Umezawa;Tsutomu Nakada;S. Hyodo;S. Hirose]
通讯作者:
Shanshan Li;A. Kato;S. Takabe;Anping Chen;M. Romero;Takahiro Umezawa;Tsutomu Nakada;S. Hyodo;S. Hirose
共 8 条
A metabolic futile cycle is operating in gas gland cells of the swimbladder.
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批准号:24657085
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
-
财政年份:2012
-
负责人:HIROSE Shigehisa
-
依托单位:
Visualization and characterization of GM2-rich lipid raft microdomain
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批准号:22657029
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.15万
-
财政年份:2010
-
负责人:HIROSE Shigehisa
-
依托单位:
Molecular characterization of chloride cells and their mechanism of differentiation
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批准号:14104002
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$72.55万
-
财政年份:2002
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负责人:HIROSE Shigehisa
-
依托单位:
Comparative molecular biology of the natriuretic peptide system (Molecular dissection and mechanism of differentiation of chloride cells)
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批准号:09102008
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项目类别:Grant-in-Aid for Specially Promoted Research
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资助金额:$100.86万
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财政年份:1997
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负责人:HIROSE Shigehisa
-
依托单位:
Developemt of protein crosslinking technology using the newly found transglutaminase substrate termed cementoin.
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批准号:05558109
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$4.8万
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财政年份:1993
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负责人:HIROSE Shigehisa
-
依托单位:
Comparative molecular biological studies on the vasoactive peptide receptors.
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批准号:04404082
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项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$14.08万
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财政年份:1992
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负责人:HIROSE Shigehisa
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依托单位:
Mechanism of Action of Atrial Natriuretic Peptide (ANP)
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批准号:63480469
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.48万
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财政年份:1988
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负责人:HIROSE Shigehisa
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依托单位:
Elucidation of the structure of angiotensin II receptor and its application to drug design
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批准号:60480467
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1985
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负责人:HIROSE Shigehisa
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依托单位:
海外基金