Characterization of basic structure and function of a new ribozyme linking groups of subviral RNA pathogen
亚病毒RNA病原体的新型核酶连接基团的基本结构和功能的表征
基本信息
- 批准号:24658036
- 负责人:
- 金额:$ 2.58万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Challenging Exploratory Research
- 财政年份:2012
- 资助国家:日本
- 起止时间:2012-04-01 至 2014-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Subviral RNA pathogen is a group of small RNA consisting of viroid which replicates autonomously depending on host transcription machinery and virus satellite RNA which replicates depending on host virus. Among them, viroid and viroid-like small circular satellite RNA are thought to be a same origin because they share similar molecular size, structure, and functions such as ribozyme activity.Here in this research, we have analyzed a new viroid-like small circular RNA isolated from mulberry (Morus alba) cultivated in China on the molecular structures, genetic diversity and new ribozyme activity found in the minus strand, and detected a couple of mutations which could change the potential of ribozyme activity. Taking the lacking of ability to replicate autonomously and the structural similarity of new ribozyme to hairpin-ribozyme in considerations, Mulberry small circular RNA can be placed in small circular viral satellite RNA group.
亚病毒RNA病原体是一类由依赖宿主转录机制自主复制的类病毒和依赖宿主病毒复制的病毒卫星RNA组成的小分子RNA。其中类病毒和类病毒小环卫星RNA由于具有相似的分子大小、结构和功能(如核酶活性)而被认为是同源的,本研究对从桑葚中分离的一种新的类病毒小环卫星RNA进行了分析(Morus alba)的分子结构、遗传多样性和新发现的负链核酶活性,并检测到几个可能改变核酶活性潜力的突变。考虑到新型核酶缺乏自主复制能力以及与发夹状核酶结构相似,桑葚小分子环状RNA可归入小分子环状病毒卫星RNA组。
项目成果
期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Molecular ecology of viroids and viroid diseases of crop plants
类病毒和作物类病毒病害的分子生态学
- DOI:
- 发表时间:2013
- 期刊:
- 影响因子:0
- 作者:Tsuda S;Sano T;高橋英樹・荒川竜行・西村光由・安藤杉尋・吉田重信・對馬誠也・百町満朗;安藤杉尋・對馬誠也・吉田重信・小林隆・伊藤豊彰・長谷修・生井恒雄・高橋英樹;Teruo Sano
- 通讯作者:Teruo Sano
Current status of viroid disease epidemics in the world
世界类病毒病流行现状
- DOI:
- 发表时间:2013
- 期刊:
- 影响因子:0
- 作者:Tsuda S;Sano T;高橋英樹・荒川竜行・西村光由・安藤杉尋・吉田重信・對馬誠也・百町満朗;安藤杉尋・對馬誠也・吉田重信・小林隆・伊藤豊彰・長谷修・生井恒雄・高橋英樹;Teruo Sano;高橋英樹・安藤杉尋・清水将文・百町満朗・岩本 豊・相野公孝・松浦克成・浅野峻介・平山喜彦・對馬誠也・吉田重信;Teruo Sano
- 通讯作者:Teruo Sano
Threats to Japanese agriculture from newly emerged plant viruses and viroids
- DOI:10.1007/s10327-013-0475-1
- 发表时间:2013
- 期刊:
- 影响因子:1.2
- 作者:S. Tsuda;T. Sano
- 通讯作者:S. Tsuda;T. Sano
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
SANO Teruo其他文献
SANO Teruo的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('SANO Teruo', 18)}}的其他基金
Pathogenicity of viroid - circular RNA pathogen; Analysis of destructive effects of viroid infection on a host miRNA/gene expression network
类病毒-环状RNA病原体的致病性;
- 批准号:
15H04455 - 财政年份:2015
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Analysis of cultivar- and tissue-specific biogenesis of viroid-specific small RNA in relation to viroid pathogenicity
与类病毒致病性相关的类病毒特异性小RNA的品种和组织特异性生物发生分析
- 批准号:
24380026 - 财政年份:2012
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Large scale sequencing analysis of microbial diversity in phyllo-and rhizo-sphares of apple trees for investigation of the mechanism to acquire natural immunity under natural farming practices
苹果树叶状和根际微生物多样性的大规模测序分析,用于研究自然农耕下获得自然免疫力的机制
- 批准号:
22658012 - 财政年份:2010
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Studies on viroid-specific RNA silencing in relation to viroid pathogenicity and molecular evolution
类病毒特异性RNA沉默与类病毒致病性和分子进化相关的研究
- 批准号:
21380029 - 财政年份:2009
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Molecular mechanisms of replication and pathogenicity of viroid -non-coding RNA pathogen
类病毒非编码RNA病原体复制和致病性的分子机制
- 批准号:
18380028 - 财政年份:2006
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Studies on viroid inducing RNA silencing from the view of plant pathology and agricultural impact
从植物病理学和农业影响的角度研究类病毒诱导的 RNA 沉默
- 批准号:
15580030 - 财政年份:2003
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
The experimental verification of viroid-host adaptation
类病毒-宿主适应的实验验证
- 批准号:
12660038 - 财政年份:2000
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of a New Gene Diagnosis Method for Plant Viruses and Viroids
植物病毒和类病毒基因诊断新方法的开发
- 批准号:
08660046 - 财政年份:1996
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Analysis of the viroid structural domains regulating viroid pathogenicity
调节类病毒致病性的类病毒结构域分析
- 批准号:
05660042 - 财政年份:1993
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
相似海外基金
ウイロイドの移行性から見る宿主範囲と作物の抵抗性
从类病毒的易位看出宿主范围和作物抗性
- 批准号:
24K08878 - 财政年份:2024
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
ウイロイド感染に対する耐病性の発揮機構の解析ーDCLの役割についてー
类病毒感染抗病机制分析-DCL的作用-
- 批准号:
23K19291 - 财政年份:2023
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Research Activity Start-up
環状RNA特異的な網羅検出技術の確立
建立针对环状RNA的综合检测技术
- 批准号:
23K18146 - 财政年份:2023
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
宿主ゲノムとウイロイドゲノムを活用した病徴予測モデルの開発
利用宿主基因组和类病毒基因组开发疾病症状预测模型
- 批准号:
21K05608 - 财政年份:2021
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Study of the molecular mechanisms involved in regulation of meristem tissue in potato tuber
马铃薯块茎分生组织调控分子机制研究
- 批准号:
21K19102 - 财政年份:2021
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
ウイロイドにおける干渉効果成立条件の解明
阐明类病毒干扰效应的条件
- 批准号:
21K14846 - 财政年份:2021
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
キク属植物をモデルとしたウイロイド抵抗性及び不定根形成メカニズムの解明
以菊花植物为模型阐明类病毒抗性和不定根形成机制
- 批准号:
20K15523 - 财政年份:2020
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Elucidation of pathogenetic expression mechanism of cyclic single-stranded RNA viroids ₋Search for target host factors₋
阐明环状单链RNA类病毒的致病表达机制
- 批准号:
19K15842 - 财政年份:2019
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Molecylar mechanism in the development of fruit disorders by viroid infection
类病毒感染导致果实病害发生的分子机制
- 批准号:
19J12238 - 财政年份:2019
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for JSPS Fellows
Establishment of a synthesis method for single-stranded circular viroid RNAs and characterization of their molecular and chemical properties
单链环状类病毒RNA合成方法的建立及其分子和化学性质的表征
- 批准号:
18K05659 - 财政年份:2018
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (C)