Novel bladder preservation therapy: BNCT-BOAI-Radiation, which selectively target cancer cells with very few complications

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We have developed the following mouse models, 1) six different mouse bladder cancer models (T24, ACHN, UMUC3, OMC-BT1, OMC-BT2, OMC-BT3) and 2) mouse baloon occluded arterial infusion model. We have been working on producing the new Boron-10 delivery system, which can be accumulated selectively in the tumor cells, especially in bladder cancer cells, using several special techniques, such as coating technique with transferrin and polyethylene glycol, lyposome-delivery technique, and coating technique with antibodies, which has a special affinity to urothelical cancer antigen.