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Study of oral biofilm associated with bacterial surface amyloid

Study of oral biofilm associated with bacterial surface amyloid
细菌表面淀粉样蛋白相关的口腔生物膜研究
批准号:
24659821
负责人:
SENPUKU Hidenobu
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31

项目摘要

项目成果

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相关文献

中文摘要
翻译
淀粉样蛋白是一种具有特定结构的不溶性纤维蛋白。很明显,这种淀粉样蛋白与革兰氏阳性细菌的生物膜形成有关。变形链球菌具有与生物膜形成有关的淀粉样蛋白。这项研究表明SMU482和SMU574可能与变形链球菌基因中的淀粉样蛋白形成有关。SMU482与生物膜的形成有关,而SMU574与生物膜的形成无关。因此,很明显淀粉样蛋白的形成不一定与生物膜的形成有关。
英文摘要
Amyloid is an insoluble fiber protein involving one specific structure. It was clealy that this amyloid was associated with the biofilm formation in gram positive bacteria.Streptococcus mutans is possessing the amyloid implicated in the biofilm formation.This study showed a posssibility that SMU482 and SMU574 associated with amyloid formation in S. mutans genes. SMU482 related with the biofilm formation but SMU574 did not related with that. Therefore, it was clearly that the amyloid formation is not necessarily concerned with biofilm formation.
期刊论文(21)
专著(0)
科研奖励(0)
会议论文
DOI: 10.7883/yoken.66.11
发表时间: 2013
期刊: Japanese journal of infectious diseases
影响因子: 2.2
作者: [Xi Zhang;H. Senpuku]
通讯作者: Xi Zhang;H. Senpuku
DOI: 10.1016/j.micinf.2013.10.005
发表时间: 2014-01-01
期刊: MICROBES AND INFECTION
影响因子: 5.8
作者: [Nakao, Ryoma, Takashiba, Shogo, Senpuku, Hidenobu]
通讯作者: Senpuku, Hidenobu
DOI: 10.1007/s00424-012-1183-y
发表时间: 2013-02-01
期刊: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
影响因子: 4.5
作者: [Satoh, Keitaro, Narita, Takanori, Sugiya, Hiroshi]
通讯作者: Sugiya, Hiroshi
DOI: --
发表时间: 2012
期刊: BMC Or al Health
影响因子: --
作者: [Norihiko Kanaguchi, Naoki Natisawa, Tatsuro Ito, Yosuke Kinoshita, Yoko Kusumoto, Osamu Shinozuka and Hidenobu Senpuku]
通讯作者: Osamu Shinozuka and Hidenobu Senpuku
13
    Development of oral biofilm-associated disease preventive agent targeting vesicle complex
    Development of control system for pathogenic oral biofilm using compound and new proteins
    • 批准号:
      21390506
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.65万
    • 财政年份:
      2009
    • 负责人:
      SENPUKU Hidenobu
    • 依托单位:
    Molecular analyses and identifications of new genes to infectious diseases relating with oral biofilm
    • 批准号:
      15390571
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.15万
    • 财政年份:
      2003
    • 负责人:
      SENPUKU Hidenobu
    • 依托单位:
    Study of susceptibility genes for oral infectious diseases relating to biofilm in elderly
    • 批准号:
      13671991
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.98万
    • 财政年份:
      2001
    • 负责人:
      SENPUKU Hidenobu
    • 依托单位:
    海外基金