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In vitro fabrication of epithelial/bone tissue complex using 3D cell construct

In vitro fabrication of epithelial/bone tissue complex using 3D cell construct
使用 3D 细胞构建体体外制造上皮/骨组织复合物
批准号:
24659874
负责人:
MATSUMOTO Takuya
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31

项目摘要

项目成果

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中文摘要
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英文摘要
The aim of this study was to fabricate cell aggregates constructed with epithelial cells and mesenchymal cells, and to lead the constructed cells to biological tissue including epithelial tissue and bone tissue.By using mesenchymal stem cell aggregates, we have succeeded in fabricating bony like tissue in vitro. Moreover, we have also succeeded in making an oriented bone formation in back of mouse by using this system. Thus, by combining with epithelial tissue layer, which is now under construction, these in vitro fabricated tissue would be a promising tool as a new implantable material.
期刊论文(14)
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会议论文
Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation
用于体外细胞和组织操作的基于水凝胶的仿生环境
DOI: --
发表时间:
期刊:
影响因子: --
作者: [Nakano A., Mishima K., Shiraishi R., Ueyama Y., 石川純,高橋伸典,山本憲幸,西川雅也,若山博隆,山口聡,日比英晴,石黒直樹,山本朗仁, Takuya Matsumoto]
通讯作者: Takuya Matsumoto
次世代歯科医療技術の開発
开发下一代牙科医疗技术
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Sasaki J, Matsumoto T, Nishiguchi M, Matsusaki M, Egusa H, Nakano T, Akashi M, Imazato S, Yatani H, 松本卓也, Matsumoto T, 松本卓也]
通讯作者: 松本卓也
Oriented bone formation using biomimetic fibrin hydrogels with three-dimensional patterned bone matrices.
使用具有三维图案骨基质的仿生纤维蛋白水凝胶定向骨形成。
DOI: 10.1002/jbm.a.35212
发表时间: 2015
期刊: Journal of Biomedical Materials Research Part A
影响因子: 4.9
作者: [Sasaki JI, Matsumoto T, Imazato S.]
通讯作者: Imazato S.
細胞周囲環境制御と細胞操作
细胞周围环境控制和细胞操纵
DOI: --
发表时间:
期刊:
影响因子: --
作者: [玉谷哲也, 高丸菜都美, 大江剛, 永井宏和, 宮本洋二, 緒方謙一,片桐渉,大杉将嗣,河合孝真,椙村有紀子,坂口晃平,日比英晴,中村誠司,上田実, 2) 松本卓也]
通讯作者: 2) 松本卓也
9
    A study of intestinal absorption mechanism of tetrodotoxin.
    • 批准号:
      25850144
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.75万
    • 财政年份:
      2013
    • 负责人:
      MATSUMOTO Takuya
    • 依托单位:
    Time-resolved electrostatic force microscopy using mechanical synchronization
    • 批准号:
      25600099
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.58万
    • 财政年份:
      2013
    • 负责人:
      MATSUMOTO Takuya
    • 依托单位:
    Creation of brain-like information devices by self-assembled redox molecular networks
    • 批准号:
      24360011
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.81万
    • 财政年份:
      2012
    • 负责人:
      MATSUMOTO Takuya
    • 依托单位:
    Development of tight adhesionsystem for implantable materials and regenerated host tissue.
    海外基金