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Development of antiviral agents targeting ATP-mediated excision

Development of antiviral agents targeting ATP-mediated excision
开发针对 ATP 介导的切除的抗病毒药物
批准号:
25670255
负责人:
Kodama Eiichi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2016-03-31

项目摘要

项目成果

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期刊论文(12)
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会议论文
Structural Basis of Inhibition and Resistance Mechanism to EFdA, a Highly Potent NRTI.
EFdA(一种高效 NRTI)的抑制和耐药机制的结构基础。
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [Zhe Li, Karen Kirby, Bruno Marchand, Michailidis Eleftherios, Eiichi Kodama, Hiroaki Mitsuya, Michael Parniak, Stefan Sarafianos.]
通讯作者: Stefan Sarafianos.
DOI: 10.1038/nchem.2308
发表时间: 2015-09-01
期刊: NATURE CHEMISTRY
影响因子: 21.8
作者: [Asai, Teigo, Tsukada, Kento, Oshima, Yoshiteru]
通讯作者: Oshima, Yoshiteru
DOI: 10.1186/1742-4690-10-65
发表时间: 2013-06-24
期刊: Retrovirology
影响因子: 3.3
作者: [Michailidis E, Ryan EM, Hachiya A, Kirby KA, Marchand B, Leslie MD, Huber AD, Ong YT, Jackson JC, Singh K, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG]
通讯作者: Sarafianos SG
Anti-HIV-1 activitydetermined byb-galactosidase activityin the multinuclear activation ofan indicator assay is comparable with that by a conventional focus counting method.
在指示剂测定的多核激活中通过β-半乳糖苷酶活性测定的抗HIV-1活性与通过传统焦点计数方法测定的抗HIV-1活性相当。
DOI: 10.1177/2040206615614164
发表时间: 2015
期刊: Antiviral Chemistry and Chemotherapy
影响因子: --
作者: [Fusako Miyamoto, Kumi Kawaji, Shinya Oishi, Nobutaka Fujii, Mitsuo Kaku, and Eiichi N.Kodama.]
通讯作者: and Eiichi N.Kodama.
6
    Development of therapeutics for intractable infections using diverse natural products combined with stress-inductive biosynthesis and chemical modification
    • 批准号:
      19H03701
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.15万
    • 财政年份:
      2019
    • 负责人:
      Kodama Eiichi
    • 依托单位:
    Novel screenings for unmet medical needs with innovative new natural product derived compounds
    • 批准号:
      16H05346
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.07万
    • 财政年份:
      2016
    • 负责人:
      Kodama Eiichi
    • 依托单位:
    海外基金