Development of antiviral agents targeting ATP-mediated excision
Development of antiviral agents targeting ATP-mediated excision
批准号:
25670255
负责人:
Kodama Eiichi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2016-03-31
中文摘要
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英文摘要
期刊论文(12)
专著(0)
科研奖励(0)
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Structural Basis of Inhibition and Resistance Mechanism to EFdA, a Highly Potent NRTI.
EFdA(一种高效 NRTI)的抑制和耐药机制的结构基础。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Zhe Li, Karen Kirby, Bruno Marchand, Michailidis Eleftherios, Eiichi Kodama, Hiroaki Mitsuya, Michael Parniak, Stefan Sarafianos.]
通讯作者:
Stefan Sarafianos.
DOI:
10.1038/nchem.2308
发表时间:
2015-09-01
期刊:
NATURE CHEMISTRY
影响因子:
21.8
作者:
[Asai, Teigo, Tsukada, Kento, Oshima, Yoshiteru]
通讯作者:
Oshima, Yoshiteru
DOI:
10.1186/1742-4690-10-65
发表时间:
2013-06-24
期刊:
Retrovirology
影响因子:
3.3
作者:
[Michailidis E, Ryan EM, Hachiya A, Kirby KA, Marchand B, Leslie MD, Huber AD, Ong YT, Jackson JC, Singh K, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG]
通讯作者:
Sarafianos SG
Anti-HIV-1 activitydetermined byb-galactosidase activityin the multinuclear activation ofan indicator assay is comparable with that by a conventional focus counting method.
在指示剂测定的多核激活中通过β-半乳糖苷酶活性测定的抗HIV-1活性与通过传统焦点计数方法测定的抗HIV-1活性相当。
DOI:
10.1177/2040206615614164
发表时间:
2015
期刊:
Antiviral Chemistry and Chemotherapy
影响因子:
--
作者:
[Fusako Miyamoto, Kumi Kawaji, Shinya Oishi, Nobutaka Fujii, Mitsuo Kaku, and Eiichi N.Kodama.]
通讯作者:
and Eiichi N.Kodama.
Sarafianos SG.Effects of substitutions at the 4' and 2 positions on the bioactivity of 4'-ethynyl-2-fluoro-2'-deoxyadenosine
Sarafianos SG.4 和 2 位取代对 4-乙炔基-2-氟-2-脱氧腺苷生物活性的影响
DOI:
--
发表时间:
2013
期刊:
Antimicrobal Agents and Chemotherapy
影响因子:
--
作者:
[Kirby KA, Michailidis E, Fetterly TL, Steinbach MA, Singh K, Marchand B, Leslie MD, Hagedorn AN, Kodama EN, Marquez VE, Hughes SH, Mitsuya H, Parniak MA]
通讯作者:
Parniak MA
共 6 条
Development of therapeutics for intractable infections using diverse natural products combined with stress-inductive biosynthesis and chemical modification
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批准号:19H03701
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.15万
-
财政年份:2019
-
负责人:Kodama Eiichi
-
依托单位:
Novel screenings for unmet medical needs with innovative new natural product derived compounds
-
批准号:16H05346
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.07万
-
财政年份:2016
-
负责人:Kodama Eiichi
-
依托单位:
海外基金