Identification of cytokines responsible for the development of immune-mediated bone marrow failure using gene expression analyses of patients with aplastic anemia
Identification of cytokines responsible for the development of immune-mediated bone marrow failure using gene expression analyses of patients with aplastic anemia
批准号:
25670448
负责人:
NAKAO Shinji
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2015-03-31
中文摘要
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英文摘要
期刊论文(10)
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DOI:
10.1056/nejmoa1414799
发表时间:
2015-07-02
期刊:
The New England journal of medicine
影响因子:
--
作者:
[Yoshizato T, Dumitriu B, Hosokawa K, Makishima H, Yoshida K, Townsley D, Sato-Otsubo A, Sato Y, Liu D, Suzuki H, Wu CO, Shiraishi Y, Clemente MJ, Kataoka K, Shiozawa Y, Okuno Y, Chiba K, Tanaka H, Nagata Y, Katagiri T, Kon A, Sanada M, Scheinberg P, Miyano S, Maciejewski JP, Nakao S, Young NS, Ogawa S]
通讯作者:
Ogawa S
Hematopoiesis in Patients with Acquired Aplastic Anemia Is Supported By a Limited Number of CXCR4(-) Cells at the Common Myeloid Progenitor Level
获得性再生障碍性贫血患者的造血功能由髓系祖细胞水平上有限数量的 CXCR4(-) 细胞支持
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Takamasa Katagiri, Atsuo Kasada, Kana Motomiya, Yoshitaka Zaimoku, An T. T. Dao, Hiroyuki Maruyama, Ken Ishiyama, Shigeki Ohtake, Atsushi Hirao, Shinji Nakao]
通讯作者:
Shinji Nakao
IncreasedHigh gene expression of Nr4A family in bone marrow T cells is associated with rapid response after ISTto cyclosoporine in the patients with non-severeearly stage acuired aplastic anemia
骨髓T细胞中Nr4A家族基因高表达与非重度早期急性再生障碍性贫血患者IST对环孢素后的快速反应相关
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Kohei Hosokawa, Takumi Nishiuchi, Takamasa Katagiri, Chizuru Saito, Hiroyuki Maruyama, Naomi Sugimori, Hirohito Yamazaki, Shinji Nakao]
通讯作者:
Shinji Nakao
Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against hematopoietic progenitor cells from a patient with severe aplastic anemia.
从患有严重再生障碍性贫血的患者中诱导具有细胞毒性和抑制造血祖细胞功能的 HLA-B*40:02 限制性 T 细胞。
DOI:
--
发表时间:
2015
期刊:
Br J Haematol
影响因子:
--
作者:
[Inaguma Y, Akatsuka Y, Hosokawa K, Maruyama H, Okamoto A, Katagiri T, Shiraishi K, Murayama Y, Tsuzuki-Iba S, Mizutani Y, Nishii C, Yamamoto N, Demachi-Okamura A, Kuzushima K, Ogawa S, Emi N, Nakao S.]
通讯作者:
Nakao S.
Imatinib for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.
伊马替尼治疗异基因造血干细胞移植后闭塞性细支气管炎。
DOI:
--
发表时间:
2015
期刊:
Bone Marrow Transplant
影响因子:
--
作者:
[Watanabe S, Waseda Y, Kimura H, Takato H, Ohata K, Kondo Y, Kasahara K, Nakao S.]
通讯作者:
Nakao S.
共 6 条
Identification of autoantigens presented by specific HLA class I alleles in aplastic anemia
-
批准号:19H03686
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2019
-
负责人:NAKAO Shinji
-
依托单位:
Identification of myelosuppressive cytokines taking advantage of genomic abnormalities of leukocytes in patients with aplastic anemia
-
批准号:24390243
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.48万
-
财政年份:2012
-
负责人:NAKAO Shinji
-
依托单位:
Identification of auto-antigens in acquired aplastic anemia associated with clonal hematopoiesis by hematopoietic stem cells with uniparental disomy of chromosome 6p
-
批准号:23659486
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:NAKAO Shinji
-
依托单位:
Identification of auto-antigens which trigger the development of immune-mediated bone marrow failure
-
批准号:21390291
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.56万
-
财政年份:2009
-
负责人:NAKAO Shinji
-
依托单位:
Identification of novel auto-antibodies and corresponding antigens in patients with aplastic anemia using CLIP replacement Ii chain library
-
批准号:19390260
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.07万
-
财政年份:2007
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of mechanisms responsible for clonal expansion of PNH-type hematopoietic stem cells mediated by autoreactive T cells in patients with bone marrow failure
-
批准号:17390275
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.79万
-
财政年份:2005
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of autoantigens in aplastic anemia : identification of an epitope recognized by CD4^+ T cells specific to hematopoietic progenitor cells
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批准号:15390298
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.85万
-
财政年份:2003
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of autoantigens in immune-mediated aplastic anemia-identification of an epitope of a CD4^+ T-cell clone
-
批准号:13470202
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.59万
-
财政年份:2001
-
负责人:NAKAO Shinji
-
依托单位:
Identification of autoantigens in autoimmune aplastic anemia
-
批准号:11670987
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.56万
-
财政年份:1999
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of heat shock protein 70 as a causal molecule of aplastic anemia
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批准号:09671103
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:1997
-
负责人:NAKAO Shinji
-
依托单位:
Isolation of T-cell clones cytotoxic agcirst nemotopoietic progenitor cells from a patienl with aplastic aremia
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批准号:06671080
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1994
-
负责人:NAKAO Shinji
-
依托单位: