Identification of myelosuppressive cytokines taking advantage of genomic abnormalities of leukocytes in patients with aplastic anemia
Identification of myelosuppressive cytokines taking advantage of genomic abnormalities of leukocytes in patients with aplastic anemia
批准号:
24390243
负责人:
NAKAO Shinji
金额:
$11.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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DOI:
10.3324/haematol.2012.066217
发表时间:
2013-06-01
期刊:
HAEMATOLOGICA
影响因子:
10.1
作者:
[Seiki, Yu, Sasaki, Yumi, Nakao, Shinji]
通讯作者:
Nakao, Shinji
Evidence That HLA-B*40:02 and HLA-Α*31:01 Are Strongly Involved in the Presentation of Autoantigens to CTLs Responsible for the Development of Acquired Aplastic Anemia
HLA-B*40:02 和 HLA-A*31:01 强烈参与向 CTL 呈递自身抗原,从而导致获得性再生障碍性贫血的证据
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Yoshitaka Zaimoku, Hiroyuki Maruyama, Kana Maruyama, Takamasa Katagiri, An T. T. Dao, Hiroyuki Takamatsu, Hirohito Yamazaki, Koichi Kashiwase, Shinji Nakao.]
通讯作者:
Shinji Nakao.
Detection of leukocytes lacking HLA-A alleles by flow cytometry predicts a response to immunosuppressive therapy in patients with acquired aplastic anemia.
通过流式细胞术检测缺乏 HLA-A 等位基因的白细胞可以预测获得性再生障碍性贫血患者对免疫抑制治疗的反应。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Hiroyuki Maruyama, Takamasa Katagiri, Kohei Hosokawa, Chizuru Saito, Hirohito Yamazaki, Shinji Nakao]
通讯作者:
Shinji Nakao
SLIT1 mutation in patients with acquired aplastic anemia : Its relevance in immune pathophysiology.
获得性再生障碍性贫血患者的 SLIT1 突变:其与免疫病理生理学的相关性。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Sakaguchi H, Yoshida K, Chizuru Saito]
通讯作者:
Chizuru Saito
Imatinib for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.
伊马替尼治疗异基因造血干细胞移植后闭塞性细支气管炎。
DOI:
--
发表时间:
2015
期刊:
Bone Marrow Transplant
影响因子:
--
作者:
[Watanabe S, Waseda Y, Kimura H, Takato H, Ohata K, Kondo Y, Kasahara K, Nakao S.]
通讯作者:
Nakao S.
共 7 条
Identification of autoantigens presented by specific HLA class I alleles in aplastic anemia
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批准号:19H03686
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2019
-
负责人:NAKAO Shinji
-
依托单位:
Identification of cytokines responsible for the development of immune-mediated bone marrow failure using gene expression analyses of patients with aplastic anemia
-
批准号:25670448
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2013
-
负责人:NAKAO Shinji
-
依托单位:
Identification of auto-antigens in acquired aplastic anemia associated with clonal hematopoiesis by hematopoietic stem cells with uniparental disomy of chromosome 6p
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批准号:23659486
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:NAKAO Shinji
-
依托单位:
Identification of auto-antigens which trigger the development of immune-mediated bone marrow failure
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批准号:21390291
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.56万
-
财政年份:2009
-
负责人:NAKAO Shinji
-
依托单位:
Identification of novel auto-antibodies and corresponding antigens in patients with aplastic anemia using CLIP replacement Ii chain library
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批准号:19390260
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.07万
-
财政年份:2007
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of mechanisms responsible for clonal expansion of PNH-type hematopoietic stem cells mediated by autoreactive T cells in patients with bone marrow failure
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批准号:17390275
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.79万
-
财政年份:2005
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of autoantigens in aplastic anemia : identification of an epitope recognized by CD4^+ T cells specific to hematopoietic progenitor cells
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批准号:15390298
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.85万
-
财政年份:2003
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of autoantigens in immune-mediated aplastic anemia-identification of an epitope of a CD4^+ T-cell clone
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批准号:13470202
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.59万
-
财政年份:2001
-
负责人:NAKAO Shinji
-
依托单位:
Identification of autoantigens in autoimmune aplastic anemia
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批准号:11670987
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.56万
-
财政年份:1999
-
负责人:NAKAO Shinji
-
依托单位:
Analysis of heat shock protein 70 as a causal molecule of aplastic anemia
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批准号:09671103
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:1997
-
负责人:NAKAO Shinji
-
依托单位:
Isolation of T-cell clones cytotoxic agcirst nemotopoietic progenitor cells from a patienl with aplastic aremia
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批准号:06671080
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1994
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负责人:NAKAO Shinji
-
依托单位:
海外基金