The relationship between oral health and the development of malnutrition in older adults – secondary data analyses of the Longitudinal Aging Study Amsterdam (LASA)

老年人营养不良是一个常见的问题，会导致负面的临床结果和增加的医疗费用。随着老年人人口的增长，老年人营养不良成为一个重要的公共卫生问题。营养不良的根源是多方面的，可能受到与健康有关的、心理或社会经济因素的影响。一个潜在的可改变的危险因素是口腔健康状况。研究表明，口腔因素与营养不良之间存在关联。然而，大多数研究是横断面的，主要调查口腔功能的单个方面，大多在机构环境中进行，而且经常在亚洲和其他新兴国家进行，这限制了研究转移到欧洲的情况。因此，本项目的目的是(A)调查社区老年人九年后口腔健康状况的不同衡量标准与营养不良事件之间的关系，以及(B)分析口腔健康状况的变化与后续期间营养状况之间的关系。阿姆斯特丹纵向老龄化研究(LASA)是一项以人群为基础的纵向试验，采用了适当的抽样程序，使样本代表了居住在荷兰的老年人。在这个项目中，将使用2007年LASA生活方式研究(n=1,054)和2015/16年度LASA浪潮的数据，因为这些调查包括关于口腔健康状况和营养状况的全面信息。为了回答研究问题，将使用多变量统计方法进行二手数据分析。

Malnutrition in older adults is a common problem leading to negative clinical outcomes and increased health care costs. As the population group of older adults is growing, malnutrition in older adults becomes an important public health issue. The origin of malnutrition is multifactorial and can be influenced by health-related, psychological or socio-economic factors. One potentially modifiable risk factor is the oral health status. Research has shown an association between oral factors and malnutrition. However, most of the studies were cross-sectional, investigated mainly single aspects of oral function, were mostly performed in institutional settings, and were often conducted in Asia and other emerging countries, limiting the transferability to the situation in Europe. Therefore, the aims of this project are (a) to investigate the relationship between different measures of oral health status and incident malnutrition after nine years in community-dwelling older adults and (b) to analyze the association between changes in oral health and nutritional status over the follow-up period. The Longitudinal Aging Study Amsterdam (LASA) is a population-based longitudinal trial that applied adequate sampling procedures making the sample representative for older adults living in the Netherlands. For this project the data of the LASA Lifestyle Study in 2007 (n=1,054) and the LASA wave of 2015/16 will be used as these investigations include comprehensive information on oral health status and nutritional status. To answer the research questions secondary data analyses will be conducted using multivariate statistical approaches.