Identification of deubiquitinases, which regulate inflammatory and immune signaling pathways, and screening for their inhibitors
Identification of deubiquitinases, which regulate inflammatory and immune signaling pathways, and screening for their inhibitors
批准号:
16K15210
负责人:
TOKUNAGA Fuminori
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2016
资助国家:
日本
项目状态:
已结题
起止时间:
2016-04-01 至 2018-03-31
中文摘要
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英文摘要
期刊论文(27)
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Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide.
DDX41的结构和功能分析:DNA和环状二核苷酸的双特异性免疫受体。
DOI:
10.1038/srep34756
发表时间:
2016-10-10
期刊:
Scientific reports
影响因子:
4.6
作者:
[Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, Tokunaga F, Nureki O]
通讯作者:
Nureki O
筋萎縮性側索硬化症(ALS)における直鎖状ユビキチン鎖の寄与
线性泛素链在肌萎缩侧索硬化症 (ALS) 中的作用
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[井田智章, 居原 秀, 守田匡伸, 笠松真吾, 松永哲郎, 西村 明, 藤井重元, 澤 智裕, 赤池孝章., 徳永文稔]
通讯作者:
徳永文稔
コムギ無細胞人プレテインアレイを基盤とした新規直鎖状ユビキチン結合タンパク質の探索と機能解析
基于小麦无细胞人蛋白阵列的新型线性泛素结合蛋白的搜索和功能分析
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[長尾和哉, 中島達朗, 高橋宏隆, 徳永文稔, 澤崎達也]
通讯作者:
澤崎達也
コムギ無細胞タンパク質アレイ解析によって見出された、NEMO結合性新規DUBのNF-κB制御機構の解析
小麦无细胞蛋白阵列分析发现的新型 NEMO 结合 DUB 的 NF-κB 调节机制分析
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[高橋宏隆, 桑田翔平, 後藤栄治, 徳永文稔, 澤崎達也]
通讯作者:
澤崎達也
大阪市立大学大学院医学研究科分子病態学
大阪市立大学医学研究科分子病理学
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 25 条
Screening for interactors of linear ubiquitin chain assembly complex (LUBAC), and studies on their physiological functions
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批准号:15H04694
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.07万
-
财政年份:2015
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Construction and application of linear ubiquitin-specific molecular probes for anti-cancer drug screening
-
批准号:25670137
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2013
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Construction of polyubiquitin chain specific molecular probes and their applications to histopathologic examinations.
-
批准号:23657075
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2011
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Investigation of physiological function of linear polyubiquitination using various biological models
-
批准号:23390070
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.73万
-
财政年份:2011
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Relationship between inflammation and novel NF-κB activation pathway which is regulated by ubiquitin system
-
批准号:20390097
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.73万
-
财政年份:2008
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Involvement of ubiquitin system on the hepatitis B virus X protein (HBx)-mediated transactivation activity
-
批准号:17590274
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2005
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Effects of HOIL-1 ubiquitin ligase complex on the physiological function of hepatitis B virus X protein
-
批准号:15590279
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.43万
-
财政年份:2003
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Studies on cellular basis of the endoplasmic reticulum-associated degradation and intracellular aggregation of misfolded proteins
-
批准号:13680695
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.83万
-
财政年份:2001
-
负责人:TOKUNAGA Fuminori
-
依托单位:
Identification of Proteins Associated with the Intracellular Degradation of Misfolded Clotting Factors
-
批准号:08680698
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.54万
-
财政年份:1996
-
负责人:TOKUNAGA Fuminori
-
依托单位:
海外基金