Molecular basis of the antifungal and antimalarial activity of a plant defensin

植物防御素抗真菌和抗疟活性的分子基础

• 批准号: LX0668974
• 负责人: Prof Marilyn Anderson
• 金额: $ 1.02万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage - International
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LX0668974
• 关键词: Molecular; basis; antifungal; antimalarial; activity

The plant defensin NaD1 has potent inhibitory activity against a number of agronomically important fungal pathogens. These species are major pathogens of cotton and other important agricultural crops such as canola and potatoes. These pathogens cause serious economic losses and threaten the future of the cotton industry in Australia. NaD1 also has potential as a new antibiotic for treatment of infections in humans.

植物防御素NaD1对许多农艺学上重要的真菌病原体具有有效的抑制活性。这些物种是棉花和其他重要农作物（如油菜和土豆）的主要病原体。这些病原菌造成了严重的经济损失，威胁着澳大利亚棉花产业的未来。NaD1也有可能成为治疗人类感染的新抗生素。