Clinician Scientist School Lübeck: Connecting Brain, Metabolism, and Inflammation (BMI) – Mechanisms and Disease Expression

吕贝克临床科学家学校：连接大脑、代谢和炎症 (BMI) â 机制和疾病表现

• 批准号: 413535489
• 负责人: Professor Dr. Christian David Sadik
• 金额: --
• 依托单位: Klinik für Dermatologie, Allergologie und Venerologie (Hautklinik)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/413535489?language=en
• 关键词: Clinician; Scientist; beck; Connecting; Brain

The University of Lübeck (UzL) is a faculty boundary-free Life Science University featuring the seamless, side-by-side collaboration between clinicians and basic scientists dedicated to translational research. The UzL prioritizes the training and integration of clinician scientists (CS) in its research. It has rigorously been pursuing the integration of research rotation positions in all of its extramurally funded research consortia. It has also established an intramural research rotation program. Obtaining one of these rotation positions is highly competitive, and the demand is significantly higher than the positions available.In collaboration with the Board of Physicians in Schleswig-Holstein, the UzL has developed a curriculum integrating clinical training and protected research time for the Board certification in Dermatology and Internal Medicine. This Board-approved curriculum nationwide is the first such program officially operating and has become a blueprint for integrated training curricula in Germany, propagated by the task force CS of the Medizinischer Fakultätentag as the Lübeck Model.To further improve the training of CS at the UzL and beyond, the establishment of centralized bodies, institution-wide orchestrating and monitoring the training of CS according to clearly defined rules and standards is imperative. Such a body, enforcing rules and training standards, is a prerequisite to implement long-lasting, Board-approved curricula through all specialties. We therefore propose to establish the Clinician Scientist School Lübeck (CSSL). The CSSL will be a UzL-wide, central infrastructure. It will coordinate, unify and monitor the training of CS. The training will be conducted according to the combined clinical/research curriculum and through a transferable skills training program. The research training of CS trainees (CST) will be interdisciplinary and conducted by mentor groups combining clinician and basic scientists. This will facilitate the training of physicians in medicine and science to lay the foundation to run both a clinic and a multidisciplinary research group. The CSSL program will also enable residents in training in scientifically emerging clinical departments to obtain training by well-established scientists outside of their department. By this, the CSSL will spread nuclei of high-quality research throughout all clinical Departments on campus.The CSTs on the requested rotation positions will conduct projects bridging the UzL research foci Brain, Behavior, and Metabolism and Infection and Inflammation. They will investigate the bidirectional crosstalk between brain, metabolism, and immune system and the mutually promoting effects of neurodegenerative, metabolic, and autoimmune disorders with genetics and omics approaches serving as an important link across projects. The specific projects and rotation positions will assigned through a competitive process including external reviewers and an internal CSSL supervisory board.

吕贝克大学（UzL）是一所教师无边界的生命科学大学，其特点是临床医生和致力于转化研究的基础科学家之间的无缝，并排合作。UzL在其研究中优先考虑临床科学家（CS）的培训和整合。它一直在严格追求在其所有的校外资助的研究财团的研究轮换职位的整合。它还建立了一个校内研究轮换计划。获得其中一个轮换职位的竞争非常激烈，需求远远高于现有的职位。与石勒苏益格-荷尔斯泰因州医师委员会合作，UzL开发了一个课程，将临床培训和保护研究时间整合在一起，以获得皮肤科和内科的委员会认证。该委员会批准的全国范围内的课程是第一个正式运作的此类计划，并已成为德国综合培训课程的蓝图，由医学专业委员会CS工作组作为吕贝克模式推广。为了进一步改善UzL及其他地区的CS培训，建立集中机构，根据明确规定的规则和标准，在整个机构范围内协调和监测CS培训是必要的。这样一个机构，执行规则和培训标准，是通过所有专业实施持久的，董事会批准的课程的先决条件。因此，我们建议建立临床科学家学校吕贝克（CSSL）。CSSL将是UzL范围内的中央基础设施。它将协调、统一和监控CS的培训。培训将根据合并的临床/研究课程并通过可转移的技能培训计划进行。CS学员（CST）的研究培训将是跨学科的，并由临床医生和基础科学家相结合的导师小组进行。这将有助于对医生进行医学和科学方面的培训，为开办诊所和多学科研究小组奠定基础。CSSL计划还将使在科学新兴临床部门接受培训的居民能够获得他们部门以外的知名科学家的培训。通过这一点，CSSL将在校园内的所有临床部门传播高质量的研究核心。在所要求的旋转位置上的CST将进行项目桥接UzL研究焦点脑，行为，代谢和感染和炎症。他们将研究大脑，代谢和免疫系统之间的双向串扰，以及神经退行性疾病，代谢和自身免疫性疾病的相互促进作用，遗传学和组学方法是跨项目的重要联系。具体的项目和轮换职位将通过竞争程序分配，包括外部评审员和内部CSSL监督委员会。