Coumarins for durable and sustainable plant protection

香豆素用于持久和可持续的植物保护

• 批准号: 415999524
• 负责人: Professor Dr. Uwe Conrath
• 金额: --
• 依托单位: Lehr- und Forschungsgebiet Biochemie und Molekularbiologie der Pflanzen
• 依托单位国家: 德国
• 项目类别: Research Grants (Transfer Project)
• 财政年份: 2019
• 资助国家: 德国
• 起止时间: 2018-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/415999524?language=en
• 关键词: Coumarins; durable; sustainable; plant; protection

Soybean is one of the most important crops worldwide. Its major diseases are Asian soybean rust, sudden death syndrome, and Sclerotinia stem rot (white mold). In the major soybean growing areas (USA, Brazil, Argentina), these diseases cause annual yield losses of several billion Euros a year. Resistant elite varieties are hardly available and cultivation practices and chemical or biological control measures are ineffective or highly expensive. Therefore, alternative measures for soybean disease control are urgently needed. Scopoletin, scoparone and ayapin are antimicrobial coumarins that are important for the disease resistance of many plants. They are almost absent from soybean. Our pilot studies demonstrate that the three coumarins can effectively fight the above-mentioned soybean diseases. Therefore, in a collaborative project with BASF Plant Science Company GmbH we aim at engineering and optimizing soybean plants with capacity to synthesize and accumulate scopoletin, scoparone, and ayapin for reducing susceptibility to Asian soybean rust, sudden death syndrome, and Sclerotinia stem rot. These plants can support reduced pesticide use in soybean production.

大豆是世界上最重要的农作物之一。主要病害有大豆锈病、猝死综合征、菌核病（白霉病）。在大豆主要种植区（美国、巴西、阿根廷），这些病害每年造成数十亿欧元的产量损失。抗性优良品种很少，栽培方法和化学或生物防治措施无效或昂贵。因此，迫切需要采取替代措施防治大豆病害。东莨菪素、天scoparone和ayapin是抗微生物香豆素，对许多植物的抗病性都很重要。它们在大豆中几乎不存在。初步研究表明，这三种香豆素能有效防治上述大豆病害。因此，在与巴斯夫植物科学有限公司的合作项目中，我们的目标是设计和优化大豆植物，使其具有合成和积累东莨菪碱、天冬酮和大豆平的能力，以降低对亚洲大豆锈病、猝死综合征和菌核菌茎腐病的易感性。这些植物可以支持减少大豆生产中农药的使用。