A study on prevention of "adult diseases" based on geographical comparison of dietary habits

基于饮食习惯地域比较的“成人病”预防研究

• 批准号: 01480207
• 负责人: HIROHATA Tomio
• 金额: $ 4.22万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1991
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-01480207/
• 关键词: epidemiology; ecological study; dietary survey; reproducibility; duplicate food study; gastric cancer; cerebro-vascular accident; high salt diet; 疫学調査; 地域差; 成人病; 食生活; 陰膳方式; 脳血管傷害

The present study was initiated to examine the association of dietary habits and chronic diseases, in particular, gastric cancer and cerebro-vascular accidents. Dietary habits were compared between high risk, intermediate risk, and low risk areas. Dietary intake was assessed by questionnaire survey as well as duplicate food study. The questionnaire survey was found very reliable by a reproducibility study interviewing a random sample of about 410 residents in one year interval in Fukuoka. Quantitative intake was assessed for 20 food or food group items. No material difference was noted for most items in different risk areas except for high salt food item. In fact, the high risk area consumed 10 times or more high salt food items than that in low risk areas. Straight line relationship was observed between salt intake from high salt diet and SMRs of gastric cancer and cerebro-vascular accidents. This finding was supported by the duplicate food study, which indicated marked geographical difference in salt consumption but no material difference for carbohydrate, fat, and protein intake. Thus, the present study strongly suggests the importance of salt intake (particularly from high salt diet) in causation of gastric cancer and cerebro-vascular accident.

本研究旨在探讨饮食习惯与慢性病，特别是胃癌和血管意外之间的关系。比较了高风险、中等风险和低风险地区的饮食习惯。膳食摄入量通过问卷调查和重复食物研究进行评估。通过对福冈市约410名居民在一年内进行随机抽样的再现性研究，发现问卷调查非常可靠。对20种食物或食物组项目的定量摄入进行了评估。除高盐食品项目外，大部分项目在不同风险地区无显著性差异。事实上，高风险地区消费的高盐食品是低风险地区的10倍或更多。高盐饮食引起的食盐摄入量与胃癌和血管意外的SMR呈直线关系。这一发现得到了重复食物研究的支持，该研究表明盐摄入量存在显著的地理差异，但碳水化合物、脂肪和蛋白质摄入量没有实质性差异。因此，本研究强烈提示盐摄入（特别是高盐饮食）在胃癌和血管意外的病因中的重要性。

项目成果

廣畑 富雄: "食生活と胃がん及び脳血管疾患に関する横断的研究" 日本衛生学会誌.

广畑富雄：《饮食习惯、胃癌和脑血管疾病的横断面研究》日本健康科学学会杂志。

廣畑 富雄: "調査票による食生活等の再現性に関する研究" 日本衛生学会誌.

Tomio Hirohata：“使用问卷调查的饮食习惯再现性研究”日本健康科学学会杂志。

廣畑 富雄: "調査票による食生活等の再現性に関する研究" 日本衛生学雑誌.

Tomio Hirohata：“使用问卷调查的饮食习惯再现性研究”日本卫生杂志。

廣畑 富雄: "福岡県民のライフスタイルについて" 癌の臨床. 33. (1992)

广畑富夫：“关于福冈居民的生活方式”癌症诊所33。（1992）

Tokunaga, S.: "The reproducibility of dietary and other data from a self -administered questionnaire used for the "life-style" survey conducted in six prefectures in Japan." Environ. Health Perspect.

Tokunaga, S.：“在日本六个县进行的‘生活方式’调查中使用的自填问卷的饮食和其他数据的可重复性。”