Syntesis and characterization of organogel-forming agents

合成了四种低分子量有机胶凝剂，用于有机液的固化。所开发的低分子量胶凝剂为（i）N-苄氧基-α-氨基酸的烷基酰胺;（ii）5-烷基-2，4，6-三氨基嘧啶和5-烷基巴比妥酸的双组分混合物;（iii）环己基-N-苄氧基-α-氨基酸的烷基酰胺。（二肽）s，和（iv）寡聚物s. N-苄氧基-L-缬氨酸和N-苄氧基-L-缬氨酸的十八烷基酰胺缬氨酰-L-缬氨酸是一种优良的胶凝剂。我们证明了一个l：5-十六烷基-2，4，6-三氨基嘧啶和5，5-双十二烷基巴比妥酸的混合物是双组分型胶凝剂的第一个实例。我们研究了20多种环二肽衍生物作为胶凝剂。通常，由不同氨基酸（例如中性和酸性）组成的环（二肽）作为胶凝剂比含有类似氨基酸的那些例如环（L-缬氨酰-L-亮氨酰）的胶凝剂优越上级。对于低聚（α-氨基酸），在溶剂中通过分子间氢键形成β-结构的低聚物具有作为胶凝剂的有用潜力。特别地，低聚（L-缬氨酸）、低聚（L-异亮氨酸）、低聚（L-苯丙氨酸）和低聚（γ-烷基-L-谷氨酸）对于硬化有机流体是良好的。

We synthesized four kinds of low-molecular-mass gelling agents to harden organic fluids. The developed low-molecular-mass gelling agents are (i) alkyl amides of N-benzyloxy-alpha-amino acids, (ii) two-componet mixture of 5-alkyl-2,4,6-triaminopyrimidine and 5-alkyl barbituric acid, (iii) cyclo (dipeptide) s, and (iv) oligo (alpha-amino acid) s.Octadecyl amides of N-benzyloxy-L-valine and N-benzyloxy-L-valyl Lvaline were foud to be ecellent gelling agents among the analogous amino acid derivatives. We showed that a l : 1 mixture of 5-hexadecyl-2,4,6-triaminopyrimidine and 5,5-didodecylbarbituric acid was the first example of two component type of gelling agent. We studied over 20 derivatives of cyclo (dipeptide) s as gelling agent. In general, cyclo (dipeptide) s consisting of differing amino acids (e.g.neutral and acidic) were superior as gelling agents to those containing similar amino acids such as cyclo (L-valyl-L-Leucyl). With respect to oligo (alpha-amino acid) s, oligomers which fomred beta-structure through intermolecular hydrogen bond in solvent had useful potential as gelling agents. In particular, oligo (L-valine), oligo (L-isoleucine), oligo(L-phenylalanine), and oligo (gamma-alkyl-L-glutamate) were good for hardening organic fluids.