Epidemiological study for onset and progression of periodontal disease.

关于牙周病的自然病史有许多研究，但疾病进展的确切性质仍不清楚。这项研究的目的是确定在三年的间隔时间内，口腔卫生状况较差的人群在没有治疗的情况下牙周状况会发生什么变化。对农村546人(男239人，女307人，初诊年龄10~44岁)进行了为期3年的监测。由于缺乏牙科设施，他们看牙医的机会很少。所有受试者都同意，他们的牙病在3年内不会得到治疗。逐个部位分析牙袋深度(PD)、附着平面(AL)、牙龈指数、菌斑分类系统、牙石指数的变化。用“Periocheck”法对上1、4、6的口腔软化部位进行了微生物学测定。“Periocheck”是检测牙龈卟啉单胞菌和齿密螺旋体的方法之一。基线平均PD男性2.37 mm，女性2.34 mm，年龄10-19岁，2.48，2.51岁，20-29岁，2.79岁，2.69岁，30-39岁，2.88岁，2.74岁，40-44岁。基线时男性平均AL为0.66 mm，10-19岁女性为0.64 mm，20-29岁为1.41，1.11岁，30-39岁为2.52，2.04岁，40-44岁为3.24，2.51。大部分PD和AL在3年内无变化。但基线时深眼袋>4 mm的AL比浅眼袋<4 mm的AL有更多的附着丧失。周期检查阳性率基线为71.4%，2年为80.2%。

There are number of studies on the natural history of periodontal disease, but exact nature of disease progress are still unclear. The purpose of this study was to determine how periodontal conditions in the population with poor oral hygiene would change without treatment during three years interval. 546 subjects (239 males and 307 females, age between 10 and 44 at initial examination) in rural area were monitored for 3 years. They have very few chances to visit dentist due to the lack of dental facilities. All of the subjects agreed that their dental diseases would not be treated over 3 years. Changes of Pocket Depth (PD) and Attachment Level (AL) Gingival Index, Plaque soring system, Calculus Index were analyzed site by site. In addition, buccomesial sites of upper 1,4,6 were determined microbiologically by using "Periocheck". "Periocheck" is one of methods that detects Porphyromonas gingivalis and Treponema denticola. Mean PD at baseline were male 2.37mm female 2.34mm at age 10-19,2.48,2.51, at age 20-29,2.79,2.69 at age 30-39,2.88,2.74 at age 40-44. Mean AL at baseline were, male 0.66mm, female 0.64mm at age 10-19,1.41,1.11 at age 20-29,2.52,2.04 at age 30-39,3.24,2.51 at age 40-44. Most of PD and AL showed any changes for 3 years. But AL with deep pocket over 4mm at baseline showed more attachment loss than AL with shallow pocket less than 4mm. Positive rate of Periocheck at baseline was 71.4% and 80.2% at 2nd year.