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Cohort Study on Management System for Periodontal Maintenance Patients.

牙周维护患者管理系统队列研究。

基本信息

批准号：
07307020
负责人：
HASEGAWA Kohji
金额：
$ 10.43万
依托单位：
Showa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1997
项目状态：
已结题

项目摘要

[Assessment of long term results after periodontal treatment]SUZUKI observed post treatment changes during maintenance period in 68 periodontal patients, and indicated that periodontal pocket keep their original depth in well maintenained group, however in down hill group recurrence of periodontal pathosis resulting in retreatment of tooth extraction occurred 32 months after treatment. KUMAGAYA surveyed post treatment changes in 208 patients. The relationships were not found between initial plaque score and post treatment results, which means host factor might be more important than parasite factor in maintenance patients.[Analysis of host factor]ISHIKAWA reported that patients who have higher antibodies to both Actinobacillus actinomycetemcomitance and porphylomonas gingivalis showed poorer post treatment results than others. MURAYAMA confirmed ISHIKAWA's observation, and suggested further that chemotactic and phagocytotic activities, total T cell number, Th/I ratio would be regarded as risk indicators for the further progression of periodontal diseases. MURAKAMI extracted high risk group which showed at least 4% further alveolar bone resorption on the X-ray pictures during 5 years from maintenance patiehts. The high risk patients exhibited significantly higher IL-l concentration in Gingival Crevicular Fluid, higher concentration of P.gingivalis in the subgingival plaque, and higher antibody titer to P.g.[Risk indicator after active periodontal treatment]HASEGAWA used a bacterial monitoring kit to detect specific enzyme for periodontopahtic bacteria such as P.g.and Treponema denticola, and concluded that this system was extremely useful in monitoring post-treatment effect. This result coincide to MURAKAMI's finding. WATANABE suggested to employ tow defferent concept in risk indicator, stage marker and state marker. Attachment level should be regarded as a stage marker and probing pocket depth as a state marker.

[牙周治疗后长期效果评估]SUZUKI观察了68名牙周患者在维持期治疗后的变化，发现维持良好组的牙周袋保持了原有的深度，但下山组在治疗后32个月出现牙周病复发，导致再次拔牙。 KUMAGAYA 调查了 208 名患者的治疗后变化。初始菌斑评分与治疗后结果之间未发现相关性，这意味着在维持治疗患者中，宿主因素可能比寄生虫因素更重要。[宿主因素分析]ISHIKAWA报道，放线杆菌伴生菌和牙龈卟啉单胞菌抗体均较高的患者，治疗后结果较差。 MURAYAMA证实了ISHIKAWA的观察，并进一步建议将趋化和吞噬活性、T细胞总数、Th/I比值视为牙周病进一步进展的危险指标。 MURAKAMI 从维持患者中提取了高风险组，该组在 5 年内的 X 射线照片上显示至少 4% 的牙槽骨进一步吸收。高危患者龈沟液中IL-l浓度显着升高，龈下菌斑中P.gingivalis浓度显着升高，P.g.抗体滴度也较高。[积极牙周治疗后的风险指标]长谷川使用细菌监测试剂盒检测P.g.和Treponema denticola等牙周病菌的特异性酶，得出结论：该系统是有效的。对于监测治疗后效果非常有用。这个结果与村上的发现相吻合。 WATANABE建议在风险指标、阶段标记和状态标记中采用两个不同的概念。附件水平应被视为阶段标记，探测袋深度应被视为状态标记。