Ecological study of Bacteroides species habored in the intestine of laboratory animals.

从小鼠、大鼠、家兔和豚鼠的盲肠内容物中分离出1080株拟杆菌科细菌。除1只NC小鼠外，其余小鼠均以优势水平分离Untypable-1组。在cf# 1小鼠中，普通螺旋体为优势种。从NC小鼠中分离出1、2、3组，但未分离出“fragilis”组和其他组。在3只BALB/c小鼠中有2只分离到脆弱杆菌。在大鼠盲肠内容物中未检出untyp1组，以普通b .和脆弱b .为优势种，其次是蛋b .和开腹b .。在豚鼠中，普通螺旋体是优势种，并从所有豚鼠中分离出来。在3只豚鼠中分别分离到均匀布氏杆菌和脆弱布氏杆菌。与其他动物相比，家兔肠道内的拟杆菌种类较多。从家兔中分离到卵形双歧杆菌、小梭菌、小梭菌。家兔中优势种为普通布蠓、均匀布蠓和脆弱布蠓，优势种为卵布蠓、蛋布蠓。小鼠分离株与大鼠分离株在生物活性水平上存在一定差异。用猪粪口服接种无菌小鼠产生的猪菌群相关小鼠中，脆弱菌群占比与正常小鼠相当，猪b型是猪肠内的优势菌种，未分离到猪b型。这些数据表明，动物可以选择最合适的拟杆菌种类。

Total 1,080 isolates of Bacteroidaceae from cecal contents of mice, rats, rabbits and guineapigs were identified by biochemical tests. Untypable-1 group was isolated at the predominant level from all mice except one of NC mice. IN CF#1 mice, B.vulgatus was dominant species. Untypable 1,2,3 groups but not "fragilis" group and other groups were isolated from NC mice. In two of three BALB/c mice, B.fragilis were isolated. In rat cecal contents, untypable-1 group was not detected and B.vulgatus and B.fragilis were predominant species and B.eggerthii and B.splanchnicus were followed. In guinea-pigs, B.vulgatus were the predominating species and isolated from all guinea-pigs. B.uniformis and B.fragilis were also isolated from one of three guinea-pigs respectively. A lot of species of Bacteroides were harbored in rabbit intestine as compared with other animal species. B.ovatus, B.thetaiotaomicron, Rikennera microfusus were isolated from only rabbits. In rabbits B.vulgatus, B.uniformis and B.fragilis were the predominating species and B.ovatus, B.eggerthii were the dominant. There were some differences on biovor level of B.vulgatus between mouse and rat isolates.In pig-flora-associated mice which were produced by oral inoculation with pig feces to germfree mice, "fragilis" group occupied as same as normal mice and B.suis which was the predominant species in pig intestine were not isolated. These data indicate that animals can select the most suitable Bacteroides species.