Effect of <Phytic Acid-Stannous Fluoride> Primer on Adhesion

我科研制了植酸-氟化亚锡底漆作为牙体修复剂，用于牙体树脂粘接剂与牙体基质的粘接。在本研究中，使用各种含有功能性单体和聚羧酸的商业水泥，研究了该底漆对粘合树脂和玻璃离子水门汀与牙齿基质、铸造陶瓷和羟基磷灰石的粘合的影响。在所有的粘接体系中，该底漆的粘接效果各不相同。此外，还获得了解释该底漆作用机理的新信息，该底漆对牙体基质中不含胶原等有机成分的铸造陶瓷和羟基磷灰石具有良好的粘接效果。这一结果表明，PYA和磷灰石之间的化学相互作用，这是一个无机组成部分的牙齿基质是有关的影响，这种底漆的粘结到牙齿。使用其中PYA盐部分地被钠取代的底漆代替PYA具有与原始底漆相同的效果，用该底漆的处理对牙齿的脱矿作用非常温和。这一结果表明，含PYA的Sn^<2+>固定牙齿基质与含功能单体或含聚羧酸的粘固剂之间的化学相互作用是该底漆对牙齿基质的主要作用，而不是其对牙齿基质的脱矿能力。该底漆的处理需要分别用PYA和SnF_2溶液两步进行。PYA和SnF_2混合的一步法引物的效果低于原来的两步法引物。这一结果也支持了该底漆的作用机理。然而，这个假设是非常复杂的。因此，该引物的作用机理还有待于进一步的研究，如电子能谱分析、红外光谱分析等。

The <Phytic acid (PYA)-Stannous Fluoride (SnF_2) > primer has been developed as the tooth conditioner for bonding of dental resin adhesives to tooth substrates in our department. In the present study, the effects of this primer on bonding of adhesive resin and glass ionomer cements to tooth substrates, castable ceramics and hydroxyapatites were examined using various commercial cements containing functional monomers and polycarboxylic acids. In all bonding-systems, this primer was vary effective. In addition, the new informations with which could explain the action mechanism of this primer were got.This primer was effective on bonding to castable ceramics and hydroxyapatites which do not contain organic components such as collargen in tooth substrates. This results suggest that the chemical interaction between PYA and apatites which is an inorganic component of tooth substrates is related to the effects of this primer on bonding to tooth. The primer in which PYA salt partially substituted with sodium, the treatment with which was very mild for demineralization to tooth, was used in place of PYA had the same effects as the original primer. This result suggests that the chemical interaction bwtween Sn^<2+> fixed tooth substrates with PYA and functional monomers or polycarboxylic acids containing cements is the main effect of this primer rather than its demineralization ability to tooth substrates. The treatment with this primer requires two steps with PYA and SnF_2 solutions, respectively. The effect of the one-step primer in which PYA and SnF_2 were mixed was lower than that of the original two-step primer. This result also supports the action mechanism of this primer mentioned above. However, this hypothesis is very complex. Therefore, further reseraches should be performed by means of instrumental analysis such as ESCA and IR specroscopy to prove the action mechanism of this primer.