Molecular Phylogeny in insectivora

食虫目分子系统发育

• 批准号: 05640789
• 负责人: KUSAKABE Shinichi
• 金额: $ 1.41万
• 依托单位: HIROSHIMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05640789/
• 关键词: Phenotrypic Evolution; Molecular Evolution; Crystalline gene; Phodopsin gene; mole

alphaA-crystallin is a major structual protein of the eye lens in most vertebrates.The Japanese mole Mogera wogura ia s mammalian species that has lost vision.In the Southern blot analysis, where part of the human alphaA-crystallin gene is used as probe, there appears a faint signal on the mole genome DNA.Its signal intensity is apparently weaker than that on the chicken genome DNA.This result suggerts an increased rate of base substitution on the mole alphaA-crystallin gene after its diversification from the ancestor of mammals.

α A-晶状体蛋白是大多数脊椎动物眼透镜的主要结构蛋白，日本鼹鼠是一种丧失视力的哺乳动物。在Southern印迹分析中，以人α A-晶状体蛋白基因的一部分作为探针，在鼹鼠基因组DNA上出现微弱的信号，其信号强度明显弱于鸡基因组DNA，这一结果表明，在其从哺乳动物的祖先多样化之后，在鼹鼠α A-晶状体蛋白基因上的取代。

项目成果

Takano, T., Kusakabe, S.and Mukai, T. :"DNA polymorphism and the origin of protein polymorphism at the Gpdh locus of Drosophila melanogaster." "Molecular Paleopopulation Biology." ed.by Takahata, N.and Clark, A.G.pp.179-190.Japan Scientific Society Press

Takano, T.、Kusakabe, S. 和 Mukai, T.：“果蝇 Gpdh 基因座的 DNA 多态性和蛋白质多态性的起源。”

Takano,T.et al.: "DNA polymorphisn and the origin of proteir polymorphism at the Gpdh locus of Drosophila melarogaster." Takahata,N.& Clark,A.G.(ed.)“Molealar Paleobiology"1993年 362pp. 179-190 (1993)

Takano, T. 等人：“果蝇 Gpdh 基因座的 DNA 多态性和蛋白质多态性起源。”Takahata, N. 和 Clark, A.G.（编辑）“Molealar Paleobiology”1993 年，179-190 页（ 1993）

Koga,A,et al.: "Distribution of polymorphic gere duplication at the Gpdh locus in natural populations of Drosophila melarogaster." Journal of Molealar Evolution. 36. 532-535 (1993)

Koga,A,et al.：“果蝇自然群体中 Gpdh 基因座多态性 Gere 重复的分布。”

Koga, A., H.Baba, S.Kusakabe, M.Hattori, and T.Mukai :"Distribution of polymorphic gene duplication at the Gpdh locus in natural populations of Drosophila melanogaster." Journal of Molecular Evolution. 36. 532-535 (1993)

Koga, A.、H.Baba、S.Kusakabe、M.Hattori 和 T.Mukai：“黑腹果蝇自然群体中 Gpdh 基因座多态性基因重复的分布。”