Molecular Phylogeny in insectivora

晶体蛋白是大多数脊椎动物晶状体的主要结构蛋白。日本鼹鼠是一种失去视力的哺乳动物。在Southern blot分析中，使用人类α -结晶蛋白基因的一部分作为探针，在鼹鼠基因组DNA上出现了微弱的信号。其信号强度明显弱于鸡基因组DNA的信号强度。这一结果表明，在鼹鼠α结晶蛋白基因从哺乳动物祖先多样化后，其碱基取代率增加。

alphaA-crystallin is a major structual protein of the eye lens in most vertebrates.The Japanese mole Mogera wogura ia s mammalian species that has lost vision.In the Southern blot analysis, where part of the human alphaA-crystallin gene is used as probe, there appears a faint signal on the mole genome DNA.Its signal intensity is apparently weaker than that on the chicken genome DNA.This result suggerts an increased rate of base substitution on the mole alphaA-crystallin gene after its diversification from the ancestor of mammals.