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Dvelopment of Adhesive Bonding Agents for Tooth Substance : Dentinal Adhesive System without Acid Etching

牙体粘合剂的开发：无酸蚀牙本质粘合系统

基本信息

批准号：
05671632
负责人：
ARAI Koichi
金额：
$ 1.41万
依托单位：
Maikai University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1993
资助国家：
日本
起止时间：
1993 至 1995
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05671632/
关键词：
Light-cured composite Dentin primer Bonding agent Dentinal adhesion SEM IR Adhesive strength

项目摘要

In this study, 151 kinds of detin primers : A-primer (60wt% hydroxyethyl methacrylate・40wt% distillled water), 50 kinds of B-primers (50 kinds of 0.5mole% amino acids were added in A-primer. respectively), 50 kinds of C-primers (10wt% pynomellitic dianhydride dimethacrylate was added in 50 kinds of B-primers respectively) and 50 kinds of D-primers (10wt% 4-acryloxyethyl trimellitic acid was added in 50 kinds of B-primers respectively), and 2 kinds of trial dentinal bonding agents were prepared. SEM observations, Infrared spectrometry and shearing adhesive test of detinusing A-, B-, C- and D-primers and trial and commercial bonding agents were examined, and the following results were obtained.1. In SEM observations and IR spectra of dentin surfaces treated with151 kinds of primers respectively, their surfaces were found dentinal tubules with smear-capping and exposed peritubular dentins, and all treatments were not occured demineralization and denaturation inorganic components in dentin.2. As for adhesive strength of detin using A-, B- and C-primers a trial dentinal bonding agent (containing 10% pynomellitic dianhydride dimethacrylate), A-, B- and C-primers had 2.5,2.5-6.0 and 6.4-10.8 MPa respectively. On the other hand, in cases of using C-primers and a commercial bonding agent, and D-primers and a new bonding agent. C- and D-primers had 10.3-13.6 and 9.5-30.2MPa respectively.3. In cases of using D-primers and a new dentinal bondig agent, this adhesive mechanism was found that their adhesive interfaces had formed the layrs of dentin-resin adhesive interfaces consisting microtags with high affinity, their results were obtained values of high strength on dentinal adhesion.

本研究共筛选出151种底物：A-底物(60wt%甲基丙烯酸羟乙酯·40wt%蒸馏水)，50种B-底物(A-底物中添加了50种0.5mmol%的氨基酸)。50种C-引发剂(在50种B引发剂中分别加入10wt%的偏苯三酸二酸二甲酯)和50种D-引发剂(在50种B引发剂中分别加入10wt%的偏苯三酸乙酯)，制备了2种牙本质粘结剂。对A、B、C、D四种底物及试验用粘合剂和市售粘合剂进行了扫描电子显微镜观察、红外光谱分析和剪切粘接试验，得到了以下结果。结果：1.在扫描电子显微镜观察和红外光谱分析中，151种引发剂处理后的牙本质表面均有牙本质小管覆盖，牙本质管周暴露，未见牙本质无机成分脱矿和变性。用A、B、C三种底物作为牙本质粘结剂(含10%邻甲基丙烯酸甲酯)，A、B、C三种底物的粘接强度分别为2.5、2.5~6.0、6.4~10.8 Mpa。另一方面，在使用C-底漆和商用粘合剂的情况下，使用D-底漆和新型粘合剂。C-型和D-型分别为10.3-13.6和9.5-30.2 Mpa。在使用D-引物和一种新型牙本质粘接剂的情况下，发现它们的粘接界面形成了由高亲和力的微标签组成的牙本质-树脂粘接界面层，其结果是获得了高强度的牙本质粘接强度。